Thon Andrea, Gamperl-Mikula Elisa, Willmitzer Florian, Leschnik Michael, Lederer Kristina Anna
Tierklinik Parndorf, VHB - Veterinaria Health Betriebs GmbH, Parndorf, Austria.
Kappa1 - Veterinary Radiology Services, Zurich, Switzerland.
JFMS Open Rep. 2024 Sep 10;10(2):20551169241273691. doi: 10.1177/20551169241273691. eCollection 2024 Jul-Dec.
A 4-year-old cat was presented with acute onset of lateralised neurological central nervous system (CNS) signs and seizures. Haematological and serum biochemical parameters were within normal limits. Imaging diagnostics revealed severe CT and MRI abnormalities of the right brain, similar to Dyke-Davidoff-Masson syndrome (DDMS) in human medicine. This syndrome includes cerebral hemiatrophy with compensatory calvarial hyperostosis and ventriculomegaly. Such changes have previously been reported only once in a single feline case of approximately the same age. In humans, DDMS is described as an embryonic and perinatal developmental disturbance or an acquired injury in early childhood.
This case report shows that without further imaging diagnostics, congenital disorders can be overlooked in some rare cases of adult cats with later onset of their first clinical signs.
一只4岁的猫出现急性发作的偏侧性中枢神经系统（CNS）体征和癫痫。血液学和血清生化参数均在正常范围内。影像学诊断显示右脑有严重的CT和MRI异常，类似于人类医学中的戴克 - 戴维多夫 - 马森综合征（DDMS）。该综合征包括脑半球萎缩伴颅骨代偿性骨质增生和脑室扩大。此前这种变化仅在一例年龄相近的猫科动物病例中报道过一次。在人类中，DDMS被描述为胚胎期和围生期发育障碍或幼儿期的后天性损伤。
本病例报告表明，在一些成年猫首次出现临床症状较晚的罕见病例中，如果没有进一步的影像学诊断，先天性疾病可能会被忽视。
