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老年患者的肛门生殖器疣:免疫衰老与新的性接触?病例报告

Anogenital Warts in Geriatrics: Immunosenescence and New Sexual Contacts? A Case Report.

作者信息

Achdiat Pati Aji, Atiyah Dini, Yulianti Fitri, Sutedja Endang, Gondokaryono Srie Prihianti, Usman Hermin Aminah, Maharani Retno Hesty

机构信息

Department of Dermatology and Venereology, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.

Department of Pathology Anatomy, Faculty of Medicine, Universitas Padjadjaran - Dr. Hasan Sadikin General Hospital, Bandung, Indonesia.

出版信息

Clin Cosmet Investig Dermatol. 2024 Sep 9;17:2045-2050. doi: 10.2147/CCID.S478391. eCollection 2024.

Abstract

INTRODUCTION

Anogenital warts (AGW) are sexually transmitted infections (STIs) caused by the human papillomavirus (HPV), particularly types 6 and 11. The highest incidence of AGW occurs in the age group of 15-24 years. However, as life expectancy increases, there is a significant rise in the geriatric population worldwide. This demographic shift is directly proportional to the increasing number of STIs cases within the geriatric group.

CASES

A case of AGW was reported in a 75-year-old man who had a history of erectile dysfunction medication use and recent sexual contact. During the physical examination, a hyperpigmented plaque with a verrucous surface was observed at the base of the penis. The results of the histopathological examination were consistent with the characteristics of AGW. In addition, HPV genotyping, through polymerase chain reaction (PCR) showed the presence of HPV type 6.

DISCUSSION

The aging process leads to a decline in immune function among geriatric individuals, which causes susceptibility to infections, including STIs. Moreover, the geriatric population has a different level of susceptibility to STIs compared to younger individuals. Factors such as physiological changes, decreased sexual function, low awareness of STIs, and having multiple sexual partners further increase the risk of STIs in this age group.

CONCLUSION

Sexual intercourse is an important component of the human life. However, the natural decline in sexual function due to the aging process often occurs with advancing age. As a result, many geriatrics seek various solutions in order to maintain sexual function and activity in old age. Since STIs can occur at any age, early detection and education are essential, particularly for the geriatric population.

摘要

引言

肛门生殖器疣(AGW)是由人乳头瘤病毒(HPV)引起的性传播感染(STI),尤其是6型和11型。AGW的发病率在15至24岁年龄组中最高。然而,随着预期寿命的增加,全球老年人口显著增加。这种人口结构的变化与老年人群中性传播感染病例数量的增加成正比。

病例

报告了一例75岁男性的AGW病例,该男性有勃起功能障碍用药史且近期有性接触。体格检查时,在阴茎根部观察到一个表面呈疣状的色素沉着斑块。组织病理学检查结果与AGW的特征相符。此外,通过聚合酶链反应(PCR)进行的HPV基因分型显示存在6型HPV。

讨论

衰老过程导致老年个体免疫功能下降,这使得他们易受包括性传播感染在内的各种感染。此外,老年人群与年轻个体相比,对性传播感染的易感性水平不同。生理变化、性功能下降、对性传播感染的认识不足以及有多个性伴侣等因素进一步增加了该年龄组中性传播感染的风险。

结论

性交是人类生活的一个重要组成部分。然而,随着年龄的增长,性功能自然下降往往会出现。因此,许多老年人寻求各种解决方案以维持老年时的性功能和性活动。由于性传播感染可发生在任何年龄,早期检测和教育至关重要,尤其是对老年人群。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc4e/11397319/55df3475f341/CCID-17-2045-g0001.jpg

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