National Center for HIV/AIDS, Viral Hepatitis, STD, and TB, Centers for Disease Control and Prevention, Atlanta, GA.
City of Philadelphia Department of Public Health, Pennsylvania.
J Infect Dis. 2019 Apr 16;219(9):1389-1397. doi: 10.1093/infdis/jiy684.
Approximately 90% of genital warts are caused by human papillomavirus (HPV) types 6 and 11. In the United States, HPV vaccination has been recommended for girls and women aged ≤26 years, and since 2011, for boys and men aged ≤21 years and for gay, bisexual, and other men who have sex with men (MSM) aged ≤26 years.
Data were obtained from 27 clinics participating in the STD Surveillance Network. Trends in the annual prevalence of anogenital warts (AGW) from 2010-2016 were described by sex and by the sex of sex partners.
During 2010-2016, significant declines in the prevalence of AGW were observed in women aged <40 years, men who have sex with women only (MSW) aged <40 years, and MSM of all age categories. An inflection in trend in 2012 was noted for MSW aged 20-24 or 25-29 years and for MSM aged 20-24 years.
The observed declines in the prevalence of AGW suggest that HPV morbidity is declining among populations attending STD clinics, including MSW, MSM, and women. Declines in younger age groups are consistent with what would be expected following the implementation of HPV vaccination. However, declines were also observed in older age groups and are not likely to be the result of vaccination.
大约 90%的生殖器疣是由人乳头瘤病毒(HPV)型 6 和 11 引起的。在美国,HPV 疫苗接种已被推荐给年龄≤26 岁的女孩和妇女,自 2011 年以来,也被推荐给年龄≤21 岁的男孩和男性以及同性恋、双性恋和其他与男性发生性关系的男性(MSM)年龄≤26 岁。
数据来自参与性传播疾病监测网络的 27 个诊所。描述了 2010-2016 年按性别和性伴侣的性别划分的肛门生殖器疣(AGW)的年度流行率趋势。
在 2010-2016 年期间,<40 岁的女性、<40 岁的仅与女性发生性关系的男性(MSW)以及所有年龄段的 MSM 中,AGW 的流行率显著下降。在 2012 年,观察到 20-24 岁或 25-29 岁的 MSW 和 20-24 岁的 MSM 的趋势出现拐点。
观察到的 AGW 流行率下降表明,在包括 MSW、MSM 和女性在内的性传播疾病诊所就诊的人群中,HPV 发病率正在下降。年轻年龄组的下降与 HPV 疫苗接种实施后预期的情况一致。然而,在年龄较大的组中也观察到下降,这不太可能是疫苗接种的结果。