Bernardini Francesco P, Skippen Brent, Cetto Raul, Calomeni Mariana, Cotofana Sebastian, Urso Simone Ugo, Paternostro Ferdinando, Hartstein Morris E
Oculoplastica Bernardini, Genoa, Milano, Italy.
Private Practice, Wagga Wagga, New South Wales, Australia.
J Cosmet Dermatol. 2025 Jan;24(1):e16582. doi: 10.1111/jocd.16582. Epub 2024 Sep 16.
The treatment of the medial infraorbital region also termed the tear trough has become increasingly popular by the use of soft tissue fillers in a minimally invasive approach using a cannula.
A total of 246 tear troughs were injected and investigated originating from 123 study participants. The clinical outcome was evaluated 6 months after the treatment by independent observers based on standardized frontal images and the procedure was documented by ultrasound imaging.
On average, 0.26 (0.1) cc [range: 0.08-0.32] of soft tissue filler material was injected per tear trough. Tear trough depth was before the treatment rated as 2.12 (0.4), whereas after the treatment it was 1.15 (0.4) (p < 0.001). Hyperpigmentation score was 2.19 (0.4) before the treatment, whereas after the treatment it was 1.31 (0.5) (p < 0.001). Intraorbital fat pseudo-prolapse severity was rated before the treatment 1.88 (0.7), whereas it was rated after the treatment 1.14 (0.3) (p < 0.001). Wrinkle severity of the lower eyelid was rated before the treatment 1.51 (0.6), whereas it was rated after the treatment 1.12 (0.3) (p < 0.001).
The results of this retrospectively investigated case series revealed that the conducted injection technique for treating the tear trough for medial infraorbital hollowing with a cannula provided statistically significant clinical improvement with a limited adverse events profile. The technique utilized an injection approach which was perpendicularly oriented to the longitudinal axis of the tear trough thereby "bridging the gap instead of filling the entire valley."
眶内侧区域(也称为泪沟)的治疗通过使用套管以微创方式注射软组织填充剂变得越来越流行。
对来自123名研究参与者的总共246个泪沟进行了注射和研究。治疗6个月后,由独立观察者根据标准化的正面图像评估临床结果,并通过超声成像记录该过程。
每个泪沟平均注射0.26(0.1)cc[范围:0.08 - 0.32]的软组织填充材料。治疗前泪沟深度评分为2.12(0.4),而治疗后为1.15(0.4)(p < 0.001)。治疗前色素沉着评分是2.19(0.4),而治疗后为1.31(0.5)(p < 0.001)。治疗前眶内脂肪假性脱垂严重程度评分为1.88(0.7),而治疗后为1.14(0.3)(p < 0.001)。治疗前下眼睑皱纹严重程度评分为1.51(0.6),而治疗后为1.12(0.3)(p < 0.001)。
这个回顾性研究的病例系列结果表明,用套管治疗眶内侧凹陷泪沟的注射技术在统计学上有显著的临床改善,且不良事件有限。该技术采用了一种与泪沟纵轴垂直的注射方法,从而“填补间隙而非填满整个凹陷”。