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C3 glomerulonephritis associated with monoclonal gammopathy of renal significance: a diagnostic and therapeutic challenge.

作者信息

Beirão Bárbara, Freitas Mariana, Silva Natália, Ferraz Patrícia, Prata Catarina, Morgado Teresa

机构信息

Centro Hospitalar de Trás-os-Montes e Alto Douro, Hospital de Vila Real, Serviço de Nefrologia, Vila Real, Portugal.

Centro Hospitalar de Trás-os-Montes e Alto Douro, Hospital de Vila Real, Serviço de Hematologia Clínica, Vila Real, Portugal.

出版信息

J Bras Nefrol. 2024 Oct-Dec;46(4):e20240092. doi: 10.1590/2175-8239-JBN-2024-0092en.

DOI:10.1590/2175-8239-JBN-2024-0092en
PMID:39284028
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11542637/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/ea7066320112/2175-8239-jbn-46-4-e20240092-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/a4b9c6ea1a00/2175-8239-jbn-46-4-e20240092-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/af8e29a2cd74/2175-8239-jbn-46-4-e20240092-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/4eb60726673e/2175-8239-jbn-46-4-e20240092-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/ea7066320112/2175-8239-jbn-46-4-e20240092-gf04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/a4b9c6ea1a00/2175-8239-jbn-46-4-e20240092-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/af8e29a2cd74/2175-8239-jbn-46-4-e20240092-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/4eb60726673e/2175-8239-jbn-46-4-e20240092-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0870/11542637/ea7066320112/2175-8239-jbn-46-4-e20240092-gf04.jpg

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本文引用的文献

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C3 glomerulopathy associated with monoclonal gammopathy: impact of chronic histologic lesions and beneficial effects of clone-targeted therapies.与单克隆丙种球蛋白血症相关的 C3 肾小球病：慢性组织学病变的影响和克隆靶向治疗的有益效果。
Nephrol Dial Transplant. 2022 Oct 19;37(11):2128-2137. doi: 10.1093/ndt/gfab302.
2
Treatment of Monoclonal Gammopathy-associated C3 Glomerulopathy With Daratumumab-based Therapy.用基于达雷妥尤单抗的疗法治疗单克隆丙种球蛋白病相关的C3肾小球病。
Clin Lymphoma Myeloma Leuk. 2021 Aug;21(8):e674-e677. doi: 10.1016/j.clml.2021.04.011. Epub 2021 Apr 23.
3
Monoclonal Gammopathy of Renal Significance.
具有肾意义的单克隆丙种球蛋白病
N Engl J Med. 2021 May 20;384(20):1931-1941. doi: 10.1056/NEJMra1810907.
4
Pathophysiology and management of monoclonal gammopathy of renal significance.肾脏相关意义单克隆免疫球蛋白病的病理生理学和治疗方法。
Blood Adv. 2019 Aug 13;3(15):2409-2423. doi: 10.1182/bloodadvances.2019031914.
5
Diagnosis and treatment of C3 glomerulopathy in a center of expertise.专业中心对C3肾小球病的诊断与治疗
Neth J Med. 2019 Jan;77(1):10-18.
6
C3 glomerulopathy - understanding a rare complement-driven renal disease.C3 肾小球病——了解一种罕见的补体驱动性肾脏疾病。
Nat Rev Nephrol. 2019 Mar;15(3):129-143. doi: 10.1038/s41581-018-0107-2.
7
The evaluation of monoclonal gammopathy of renal significance: a consensus report of the International Kidney and Monoclonal Gammopathy Research Group.肾脏意义单克隆丙种球蛋白病的评估：国际肾脏病和单克隆丙种球蛋白病研究小组的共识报告。
Nat Rev Nephrol. 2019 Jan;15(1):45-59. doi: 10.1038/s41581-018-0077-4.
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Both Monoclonal and Polyclonal Immunoglobulin Contingents Mediate Complement Activation in Monoclonal Gammopathy Associated-C3 Glomerulopathy.单克隆和多克隆免疫球蛋白成分均可介导单克隆丙种球蛋白病相关 C3 肾小球病中的补体激活。
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C3 Glomerulopathy: Ten Years' Experience at Mayo Clinic.C3 肾小球病：梅奥诊所十年经验。
Mayo Clin Proc. 2018 Aug;93(8):991-1008. doi: 10.1016/j.mayocp.2018.05.019.
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