Yamanaka Masashi, Mori Yutaro, Matsumoto Kazuki, Moriya Shunsuke, Yamano Akihiro, Shimo Takahiro, Shirata Ryosuke, Nitta Kazunori, Nagata Hironori, Tokuuye Koichi
Department of Medical Physics, Shonan Kamakura General Hospital, Kamakura, Kanagawa, Japan.
Institute of Medicine, University of Tsukuba, Tsukuba, Ibaraki, Japan.
J Appl Clin Med Phys. 2024 Dec;25(12):e14525. doi: 10.1002/acm2.14525. Epub 2024 Sep 16.
In the modeling of beam data for proton therapy planning systems, absolute dose measurements are performed utilizing a Bragg peak chamber (BPC), which is a parallel-plate ionization chamber. The long-term stability of the BPC is crucial for ensuring accurate absolute dose measurement. The study aims to assess the long-term stability of the BPC in clinical proton pencil beam scanning delivery.
The long-term stability evaluation focused on the BPC-Type 34070 (PTW Freiburg, Germany), utilizing clinical proton scanning beams from December 2022 to November 2023. Monthly investigations were conducted to evaluate the response and cross-calibration factor of the BPC and a reference chamber, employing the spread-out Bragg peak (SOBP) field. Additionally, assessments were made regarding the BPC's response to monoenergetic beams, along with an examination of the impact of polarity and ion recombination on the BPC.
The response and cross-calibration factor of the BPC varied up to 1.9% and 1.8%, respectively, while the response of the reference chamber remained within a 0.5% range. The BPC's response to the mono-energetic beams varied up to 2.0% across all energies, demonstrating similar variation trends in both the SOBP field and mono-energetic beams. Furthermore, the variations in polarity and ion recombination effect remained stable within a 0.4% range throughout the year. Notably, the reproducibility of the BPC remained high for each measurement conducted, whether for the SOBP field or mono-energetic beams, with a maximum deviation observed at 0.1%.
The response and cross-calibration factor of the BPC demonstrated significant variations, with maximum changes of 1.9% and 1.8%, respectively. However, the reproducibility of the BPC remained consistently high for each measurement. It is recommended that when conducting absolute dose measurements using a BPC, its response should be compared and corrected against the reference chamber for each measurement.
在质子治疗计划系统的射束数据建模中,利用布拉格峰电离室(BPC)进行绝对剂量测量,该电离室为平行板电离室。BPC的长期稳定性对于确保准确的绝对剂量测量至关重要。本研究旨在评估BPC在临床质子笔形束扫描治疗中的长期稳定性。
长期稳定性评估聚焦于34070型BPC(德国弗莱堡PTW公司),使用2022年12月至2023年11月的临床质子扫描射束。每月进行调查,利用扩展布拉格峰(SOBP)射野评估BPC和参考电离室的响应及交叉校准因子。此外,还评估了BPC对单能射束的响应,以及极性和离子复合对BPC的影响。
BPC的响应和交叉校准因子分别变化高达1.9%和1.8%,而参考电离室的响应保持在0.5%范围内。BPC对单能射束的响应在所有能量下变化高达2.0%,在SOBP射野和单能射束中均呈现相似的变化趋势。此外,极性和离子复合效应的变化在全年内保持在0.4%范围内稳定。值得注意的是,无论对于SOBP射野还是单能射束,每次测量时BPC的重现性都很高,最大偏差为0.1%。
BPC的响应和交叉校准因子显示出显著变化,最大变化分别为1.9%和1.8%。然而,BPC每次测量的重现性始终很高。建议在使用BPC进行绝对剂量测量时,每次测量都应将其响应与参考电离室进行比较并校正。