Suppr超能文献

墨西哥儿童因铅暴露导致认知功能丧失及其相关经济成本。

Loss of cognitive function in Mexican children due to lead exposure and the associated economic costs.

机构信息

Centro de Investigación en Evaluación y Encuestas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.

Centro de Investigación en Evaluación y Encuestas, Instituto Nacional de Salud Pública, Cuernavaca, Morelos, Mexico.

出版信息

Environ Res. 2024 Dec 15;263(Pt 1):120013. doi: 10.1016/j.envres.2024.120013. Epub 2024 Sep 14.

Abstract

BACKGROUND

Lead exposure reduces the cognitive development and future economic prospects of children. While previous studies in high-income settings have explored productivity losses associated with lead exposure, limited research has focused on low and middle-income countries like Mexico.

OBJECTIVES

This study aims to provide a comprehensive assessment of the economic implications of lead exposure on Mexican children using, for the first time, nationally representative Blood Lead Levels (BLLs) measurements in children aged 1-4, specifically focusing on the costs of forgone lifetime income due to cognitive losses.

METHODS

BLLs of children aged 1-4 were extracted from the 2018-2019 National Health and Nutrition Survey (ENSANUT). Estimations of cognitive losses were derived from a log-linear relationship between BLLs and IQ loss. Lost lifetime economic productivity per child was calculated, assuming a 2% reduction in lifetime potential productivity for each IQ point lost due to lead exposure, based on previous literature (Attina and Trasande, 2013; Larsen and Sánchez-Triana, 2023). Productivity data were obtained from representative sources for Mexico.

RESULTS

The estimated economic loss amounted to US $33.02 billion, equivalent to 2.76% of Mexico's Gross Domestic Product (GDP) in 2019 (calculated for a 1-year cohort). On a national scale, the long-term loss of cognition for children 1-4 years old is 4.14 IQ points per child due to lead exposure, with significant variability across States (range: 3.26 to 5.26). Lead-poisoned children (≥5 μg/dL) suffered an average loss of 6.42 IQ points (range: 0 to 6.97). In terms of economic impact, some States like Chiapas experienced losses of 7.08% of its GDP, while others had losses as low as 0.67%. Intriguingly, states with lower Human Development Index (HDIs) exhibited relatively higher economic losses despite lower average blood lead levels.

DISCUSSION

The heterogeneous impact of lead exposure across Mexican states underscores the necessity for tailored regional policies. These findings emphasize the urgency for targeted interventions and informed policy measures to mitigate the socioeconomic consequences of lead exposure on Mexican children.

摘要

背景

铅暴露会降低儿童的认知发展和未来的经济前景。虽然高收入环境中的先前研究已经探讨了与铅暴露相关的生产力损失,但针对墨西哥等中低收入国家的研究有限。

目的

本研究旨在利用墨西哥儿童的全国代表性血铅水平(BLL)测量值(首次使用),全面评估铅暴露对墨西哥儿童的经济影响,特别关注因认知损失而导致的终生收入损失成本。

方法

从 2018-2019 年国家健康和营养调查(ENSANUT)中提取了 1-4 岁儿童的 BLL 数据。通过 BLL 与智商损失之间的对数线性关系来估计认知损失。假设由于铅暴露导致每失去一个 IQ 点,终生潜在生产力减少 2%,从而计算每个儿童的终生经济生产力损失,这是基于先前的文献(Attina 和 Trasande,2013;Larsen 和 Sánchez-Triana,2023)。从代表墨西哥的来源获取生产力数据。

结果

估计的经济损失达到 330.2 亿美元,相当于 2019 年墨西哥国内生产总值(GDP)的 2.76%(计算为 1 年队列)。在全国范围内,由于铅暴露,1-4 岁儿童的长期认知损失为每个儿童 4.14 个 IQ 点,各州之间存在显著差异(范围:3.26 至 5.26)。铅中毒儿童(≥5μg/dL)平均损失 6.42 个 IQ 点(范围:0 至 6.97)。就经济影响而言,恰帕斯州等一些州损失了其 GDP 的 7.08%,而其他州的损失则低至 0.67%。有趣的是,尽管平均血铅水平较低,但人类发展指数(HDI)较低的州的经济损失相对较高。

讨论

墨西哥各州之间铅暴露的异质性影响突出了制定有针对性的区域政策的必要性。这些发现强调了采取有针对性的干预措施和制定明智政策措施的紧迫性,以减轻铅暴露对墨西哥儿童的社会经济后果。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验