2015年至2016年中国上海胆道闭锁的发病率及转归：一项队列研究
Incidence and outcome of biliary atresia in Shanghai, China from 2015 to 2016: a cohort study.
作者信息
Yang Yifan, Dong Rui, Chen Gong, Zheng Shan, Yan Weili, Shen Zhen
机构信息
Department of Pediatric Surgery, Children's Hospital of Fudan University, Shanghai, China.
Department of Clinical Epidemiology & Clinical Trial Unit (CTU), Children's Hospital of Fudan University, Shanghai, China
出版信息
BMJ Paediatr Open. 2024 Sep 16;8(1):e002475. doi: 10.1136/bmjpo-2023-002475.
Demographic characteristics and clinical data of all newly diagnosed biliary atresia patients in Shanghai were collected from 1 January 2015 to 31 October 2016. The total number of live births was 377 420 during the study period, and the incidence of biliary atresia in Shanghai was 10.86 per 100 000 (95% CI 7.8 to 17.74), with 62.9% and 45.7% cases retaining native liver survival at 2 and 5 years after Kasai procedure, respectively. Implementation of systematic screening measures for biliary atresia in China is needed.
收集了2015年1月1日至2016年10月31日期间上海所有新诊断的胆道闭锁患者的人口统计学特征和临床数据。研究期间活产总数为377420例，上海胆道闭锁的发病率为每10万人中10.86例（95%置信区间7.8至17.74），分别有62.9%和45.7%的病例在葛西手术后2年和5年保留了自身肝脏存活。中国需要实施胆道闭锁的系统筛查措施。
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