Department of Enterprise Engineering, University of Rome Tor Vergata, Via del Politecnico 1, Rome, 00133, Italy.
Department of Enterprise Engineering, University of Rome Tor Vergata, Via del Politecnico 1, Rome, 00133, Italy; SINTEF Digital, Professor Brochs Gate 2, Trondheim, 7030, Norway.
Med Eng Phys. 2024 Sep;131:104229. doi: 10.1016/j.medengphy.2024.104229. Epub 2024 Aug 16.
The pre-operative planning and intra-operative navigation of the endovascular aneurysm repair (EVAR) procedure are currently challenged by the aortic deformations that occur due to the insertion of a stiff guidewire. Hence, a fast and accurate predictive tool may help clinicians in the decision-making process and during surgical navigation, potentially reducing the radiations and contrast dose. To this aim, we generated a reduced order model (ROM) trained on parametric finite element simulations of the aortic wall-guidewire interaction.
A Design of Experiments (DOE) consisting of 300 scenarios was created spanning over seven parameters. Radial basis functions were used to achieve a morphological parametrization of the aortic geometry. The ROM was built using 200 scenarios for training and the remaining 100 for validation.
The developed ROM estimated the displacement of aortic nodes with a relative error below 5.5% for all the considered validation cases. From a preliminary analysis, the aortic elasticity, the stiffness of the guidewire and the tortuosity of the cannulated iliac artery proved to be the most influential parameters.
Once built, the ROM provided almost real-time and accurate estimations of the guidewire-induced aortic displacement field, thus potentially being a promising pre- and intra-operative tool for clinicians.
血管内动脉瘤修复(EVAR)手术的术前规划和术中导航目前受到因插入硬导丝而导致的主动脉变形的挑战。因此,快速准确的预测工具可能有助于临床医生在决策过程中和手术导航期间,潜在地减少辐射和对比剂量。为此,我们基于主动脉壁-导丝相互作用的参数有限元模拟生成了一个降阶模型(ROM)。
创建了一个包含 300 个场景的实验设计(DOE),涵盖了七个参数。径向基函数用于实现主动脉几何形状的形态参数化。ROM 使用 200 个场景进行训练,其余 100 个场景用于验证。
开发的 ROM 以低于 5.5%的相对误差估计了所有考虑的验证案例中主动脉节点的位移。初步分析表明,主动脉弹性、导丝刚度和带套管髂动脉的迂曲度是最具影响力的参数。
ROM 一旦建立,就可以提供导丝诱导的主动脉位移场的近乎实时和准确估计,因此有望成为临床医生术前和术中的有前途的工具。