Taylor Sophia, Handy Scott T
Department of Chemistry, Middle Tennessee State University, Murfreesboro, TN, USA.
Beilstein J Org Chem. 2024 Sep 2;20:2217-2224. doi: 10.3762/bjoc.20.189. eCollection 2024.
Electrosynthesis is a technique that is attracting increased attention and has many appealing features, particularly its potential greenness. At the same time, electrosynthesis requires a solvent and a supporting electrolyte in order for current to pass through the reaction. These are effectively consumable reagents unless a convenient means of recycling can be developed. As part of our interest in unusual solvents and electrochemistry, we explored the application of simple, inexpensive, and recyclable deep eutectic solvents to the allylation of carbonyls. While several sets of conditions were developed, the goal of avoiding stoichiometric amounts of metal has proven elusive. Still, a deep eutectic solvent can be used to plate out and thus recover the metal used, offering an interesting new option for electrochemical allylations.
电合成是一种正吸引着越来越多关注且具有许多吸引人特性的技术，尤其是其潜在的绿色环保性。与此同时，电合成需要一种溶剂和一种支持电解质以使电流通过反应。除非能开发出便捷的回收方法，否则这些实际上都是可消耗的试剂。作为我们对特殊溶剂和电化学感兴趣的一部分，我们探索了简单、廉价且可回收的深共熔溶剂在羰基烯丙基化反应中的应用。虽然开发了几套条件，但避免使用化学计量的金属这一目标仍难以实现。不过，深共熔溶剂可用于电镀从而回收所使用的金属，为电化学烯丙基化反应提供了一个有趣的新选择。
