Department of Cardiology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Medicine (Baltimore). 2024 Sep 13;103(37):e39698. doi: 10.1097/MD.0000000000039698.
The purpose of this research was to assess the association between sleep disorders and coronary heart disease (CHD) using data from the National Health and Nutrition Examination Survey (NHANES) database. This cross-sectional study included 9886 eligible participants with valid data on sleep disorders and CHD from the NHANES from 2011 to 2014. The complex NHANES sampling led to use of sample weights in analyses. Various statistical methods and covariates were utilized. Significance was set at P < .05. Receiver operating characteristic curves were used to assess the diagnostic efficacy of sleep disorders in relation to CHD. Sleep disorders were significantly associated with CHD (P < .001). In the model corrected for age, sex, race, hypertension, diabetes, and uric acid as covariates, sleep disorders and CHD remained significantly associated (P < .001, odds ratio = 1.83 [95% confidence interval: 1.31-2.58]). The correlation between sleep disorders and CHD varies by age and gender. Sleep disorders have some predictive value for CHD (0.5 < area under curve ≤ 0.7). Sleep disorders were associated with and predictive of CHD risk, warranting consideration in clinical assessments.
本研究旨在利用国家健康和营养调查（NHANES）数据库的数据评估睡眠障碍与冠心病（CHD）之间的关联。这项横断面研究纳入了 9886 名符合条件的参与者，他们在 2011 年至 2014 年的 NHANES 中均有睡眠障碍和 CHD 的有效数据。由于采用了复杂的 NHANES 抽样方法，因此在分析中使用了样本权重。采用了各种统计方法和协变量。显著性水平设为 P<0.05。采用受试者工作特征曲线评估睡眠障碍与 CHD 相关的诊断效能。睡眠障碍与 CHD 显著相关（P<0.001）。在模型中校正年龄、性别、种族、高血压、糖尿病和尿酸作为协变量后，睡眠障碍与 CHD 仍显著相关（P<0.001，比值比=1.83[95%置信区间：1.31-2.58]）。睡眠障碍与 CHD 之间的相关性随年龄和性别而变化。睡眠障碍对 CHD 有一定的预测价值（0.5<曲线下面积≤0.7）。睡眠障碍与 CHD 风险相关，并可预测 CHD 风险，在临床评估中值得考虑。
