Department of Surgery, The George Washington University Hospital, Washington, District of Columbia, USA.
Department of General Surgery, Walter Reed National Military Medical Center, Bethesda, Maryland, USA.
J Laparoendosc Adv Surg Tech A. 2024 Sep;34(9):798-807. doi: 10.1089/lap.2024.0281.
The treatment of non-small cell lung cancer (NSCLC) has evolved tremendously in recent decades as innovations in medical therapies advanced concomitantly with minimally invasive surgical techniques. Despite early skepticism regarding its benefits, video-assisted thoracoscopic surgery (VATS) techniques for the surgical resection of early-stage NSCLC have now become the standard of care. After being the subject of many studies since its inception, VATS has been shown to cause less postoperative pain, have shorter recovery time, and have fewer overall complications when compared to conventional open approaches. Furthermore, some studies have shown it to have comparable oncological outcomes, though more higher evidence studies are needed. Newer technologies and improved surgical instruments, advancements in nodule localization techniques, and improved preoperative staging procedures have allowed for the development of newer, less invasive techniques such as uniportal VATS and parenchymal-sparing sublobar resections, which might further improve postoperative rates of complications in specific cases. These minimally invasive approaches have allowed surgeons to offer surgery to high-risk patients and those who would otherwise not tolerate conventional thoracotomy, though some relative contraindications still exist. This review aims to describe the evolution of VATS lobectomy, current techniques, its indications, contraindications, preoperative testing, benefits, and outcomes in patients with stage I and II NSCLC.
在过去的几十年中,随着医学治疗的创新与微创外科技术的同步发展,非小细胞肺癌(NSCLC)的治疗取得了巨大的进展。尽管最初对其益处存在怀疑,但现在电视辅助胸腔镜手术(VATS)技术已成为早期 NSCLC 手术切除的标准治疗方法。自成立以来,经过多项研究,VATS 已被证明与传统的开放性方法相比,术后疼痛更少,恢复时间更短,总体并发症更少。此外,一些研究表明其具有相似的肿瘤学结果,但需要更多的高级证据研究。新技术和改进的手术器械、结节定位技术的进步以及改进的术前分期程序,使得诸如单端口 VATS 和部分肺叶切除术等更新、更微创的技术得以发展,这些技术可能会进一步降低特定情况下的术后并发症发生率。这些微创方法使外科医生能够为高危患者和那些无法耐受传统开胸手术的患者提供手术,但仍存在一些相对禁忌症。本文旨在描述 VATS 肺叶切除术的发展、当前技术、其适应证、禁忌证、术前检查、优势以及在 I 期和 II 期 NSCLC 患者中的结果。