Maehara Y, Sakaino K, Nozaki M, Matsumoto M, Satake B, Makino S, Matsuura S
Gan No Rinsho. 1985 Jul;31(8):901-7.
From May 1979 to December 1982, 31 patients with reappraisable preoperative CT were treated with trimodal combination therapy for maxillary sinus squamous cell carcinoma. The three-year cumulative survival rate of all cases was 43% and the two-year cumulative local control rate was 44%. The 5-FU distribution in infusion chemotherapy was reappraised by the dye method and the radiation field was reappraised on the basis of preoperative CT. Only patients who received suitable infusion chemotherapy and radiotherapy showed a good local control rate. Suitably performed infusion chemotherapy and radiotherapy were essential in our trimodal combination therapy. Radiotherapy must be planned according to the individual patient on the basis of the preoperative CT and surgical findings.
1979年5月至1982年12月,31例术前CT可重新评估的上颌窦鳞状细胞癌患者接受了三联综合治疗。所有病例的三年累积生存率为43%,两年累积局部控制率为44%。通过染料法重新评估了灌注化疗中的5-氟尿嘧啶分布,并在术前CT的基础上重新评估了放射野。只有接受了合适的灌注化疗和放疗的患者才显示出良好的局部控制率。在我们的三联综合治疗中,适当进行的灌注化疗和放疗至关重要。放疗必须根据术前CT和手术结果,针对个体患者进行规划。