Kunstýr I, Naumann S
Lab Anim. 1985 Jul;19(3):208-13. doi: 10.1258/002367785780893548.
Rabbits (Oryctolagus cuniculus) of non-dwarf (Group A) and dwarf (Group B) strains showing a common clinical sign of head tilt (torticollis) were examined. With 1 exception, all rabbits of group A had otitis and empyema of either one or both middle ears. Pasteurella multocida was isolated from pus and from the nose of all but 1 of these rabbits, and on occasion was also isolated from the brain. By contrast in all dwarf rabbits the presence of the protozoan Encephalitozoon cuniculi was confirmed both histologically and serologically. This parasite did not affect the ears of the animals but rather the central nervous system. We assume that the different exposure to both agents, rather than the degree of susceptibility, was responsible for the differences found between the 2 types of rabbits.
对表现出头部倾斜(斜颈)这一常见临床症状的非侏儒(A组)和侏儒(B组)品系的兔子(穴兔)进行了检查。A组除1只兔子外,所有兔子均患有单侧或双侧中耳中耳炎和积脓。多杀巴斯德菌从除1只兔子外的所有这些兔子的脓液和鼻子中分离出来,偶尔也从大脑中分离出来。相比之下,在所有侏儒兔中,通过组织学和血清学方法均证实存在兔脑原虫。这种寄生虫不影响动物的耳朵,而是影响中枢神经系统。我们认为,两种兔子之间发现的差异是由于对这两种病原体的不同暴露,而非易感性程度不同所致。