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年龄、性别、合并症及抗血栓药物的使用对因膀胱填塞接受手术治疗患者临床病程严重程度的影响。

The impact of age, sex, comorbidities, and use of antithrombotics on the clinical course severity among patients surgically treated for urinary bladder tamponade.

作者信息

Jakus Dora, Šitum Marijan, Čepin Petra, Vrhovac Ivana, Borovac Josip Anđelo

机构信息

Department of Urology, University Hospital of Split, Split, Croatia.

Cardiovascular Diseases Department, University Hospital of Split, Split, Croatia.

出版信息

Urol Ann. 2024 Jul-Sep;16(3):192-196. doi: 10.4103/ua.ua_70_23. Epub 2024 Jul 3.

Abstract

OBJECTIVES

To examine the relationship between clinical patient characteristics and the severity of the disease course in patients hospitalized due to urinary bladder tamponade. The severity was assessed based on hemoglobin (Hgb) levels upon admission, the requirement for red blood cell transfusion (RBCT), and length of hospital stay.

MATERIALS AND METHODS

A retrospective analysis was conducted at a single center, involving 75 patients who were hospitalized due to urinary bladder tamponade.

RESULTS

Bladder cancer (33.3%) and postoperative bleeding (28%) were the most common causes of bladder tamponade. Patient age exhibited a negative correlation with Hgb levels upon admission ( = -0.539, < 0.001) and a positive correlation with the quantity of administered RBCT units ( = 0.425, < 0.001) and the length of hospitalization ( = 0.541, < 0.001). The number of comorbidities exhibited a negative correlation with Hgb levels upon admission ( = -0.555, < 0.001) and a positive correlation with the quantity of administered RBCT units ( = 0.522, < 0.001) and the length of hospitalization ( = 0.543, < 0.001). Patients taking antithrombotic therapy (AT) had lower mean Hgb levels on admission (87.8 ± 13.5 g/L vs. 107.6 ± 18.7 g/L, < 0.001), a higher mean number of administered RBCT units (2.8 ± 2.1 vs. 1.1 ± 1.3, < 0.001) and longer hospitalizations (4.6 ± 1.6 days vs. 3.1 ± 1.1 days, < 0.001) compared to those not taking AT.

CONCLUSION

Older patients with multiple comorbidities, particularly those taking AT, should be expected to have a more severe clinical course of bladder tamponade. Therefore, special clinical attention is necessary for this vulnerable patient group.

摘要

目的

探讨因膀胱填塞住院患者的临床特征与病程严重程度之间的关系。根据入院时血红蛋白(Hgb)水平、红细胞输注(RBCT)需求及住院时间评估严重程度。

材料与方法

在单一中心进行回顾性分析,纳入75例因膀胱填塞住院的患者。

结果

膀胱癌(33.3%)和术后出血(28%)是膀胱填塞最常见的原因。患者年龄与入院时Hgb水平呈负相关(=-0.539,<0.001),与RBCT输注量呈正相关(=0.425,<0.001),与住院时间呈正相关(=0.541,<0.001)。合并症数量与入院时Hgb水平呈负相关(=-0.555,<0.001),与RBCT输注量呈正相关(=0.522,<0.001),与住院时间呈正相关(=0.543,<0.001)。与未接受抗血栓治疗(AT)的患者相比,接受AT治疗的患者入院时平均Hgb水平较低(分别为87.8±13.5 g/L和107.6±18.7 g/L,<0.001),平均RBCT输注量较高(分别为2.8±2.1和1.1±1.3,<0.0,01),住院时间更长(分别为4.6±1.6天和3.1±1.1天,<0.001)。

结论

合并多种疾病的老年患者,尤其是接受AT治疗的患者,膀胱填塞的临床病程可能更严重。因此,应对这一脆弱患者群体给予特别的临床关注。

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