膀胱癌的分级和侵袭性对因膀胱癌出血导致膀胱填塞的患者疾病进程严重程度的影响。
Influence of the grade and invasiveness of bladder cancer on disease course severity in patients with bladder tamponade resulting from a bleeding bladder cancer.
作者信息
Jakus Dora, Čepin Petra, Vrhovac Ivana, Jakus Ivana Alujević
机构信息
Department of Urology, University Hospital Center Split, Split, Croatia.
Department of Gynecology and Obstetrics, University Hospital Center Split, Split, Croatia.
出版信息
Urol Ann. 2023 Jan-Mar;15(1):27-30. doi: 10.4103/ua.ua_181_21. Epub 2022 Nov 8.
INTRODUCTION AND OBJECTIVES
Urinary bladder tamponade is a common urological emergency, but it has so far been insufficiently researched. The aim of our study was to show the association between the characteristics of bladder cancer (grade and invasiveness) and disease course severity based on blood hemoglobin (Hgb) count at admission, the need for red blood cell transfusion (RBCT), and the length of hospitalization in patients suffering from bladder tamponade.
MATERIALS AND METHODS
A retrospective, cross-sectional study was conducted, namely, including 25 adult patients surgically treated for bladder tamponade resulting from a bleeding bladder cancer.
RESULTS
Patients with low-grade cancer had statistically significantly higher mean Hgb values at admission (101.14 ± 8.26 vs. 87.22 g/L ± 10.64 g/L, = 0.005), as well as a lower mean number of received units of RBCT (0.71 ± 0.76 vs. 2.39 ± 1.46, < 0.001) and a shorter hospitalization (2.43 ± 0.55 vs. 4.36 ± 1.04 days, = 0.009) than those with high-grade cancer. Patients suffering from nonmuscle-invasive bladder cancer (NMIBC) had statistically significantly higher mean Hgb values at admission (96.69 ± 9.86 g/L vs. 81.22 ± 7.23 g/L, = 0.001), as well as a lower mean number of received units of RBCT (1.31 ± 1.2 vs. 3 ± 1.41, = 0.004) and a shorter hospitalization (3.31 ± 1.14 vs. 4.78 ± 0.97 days, = 0.004) than those with muscle-invasive bladder cancer.
CONCLUSION
Low-grade bladder cancer and NMIBC are associated with a milder clinical course of bladder tamponade.
引言与目的
膀胱填塞是一种常见的泌尿外科急症，但迄今为止研究尚不充分。我们研究的目的是基于入院时的血红蛋白（Hgb）计数、红细胞输注（RBCT）需求以及膀胱填塞患者的住院时间，来展示膀胱癌特征（分级和侵袭性）与疾病进程严重程度之间的关联。
材料与方法
进行了一项回顾性横断面研究，纳入了25例因膀胱癌出血接受手术治疗的成年膀胱填塞患者。
结果
低级别癌症患者入院时的平均Hgb值在统计学上显著更高（101.14±8.26 vs. 87.22 g/L±10.64 g/L，P = 0.005），接受RBCT的平均单位数更低（0.71±0.76 vs. 2.39±1.46，P < 0.001），住院时间更短（2.43±0.55 vs. 4.36±1.04天，P = 0.009），均优于高级别癌症患者。非肌层浸润性膀胱癌（NMIBC）患者入院时的平均Hgb值在统计学上显著更高（96.69±9.86 g/L vs. 81.22±7.23 g/L，P = 0.001），接受RBCT的平均单位数更低（1.31±1.2 vs. 3±1.41，P = 0.004），住院时间更短（3.31±1.14 vs. 4.78±0.97天，P = 0.004），均优于肌层浸润性膀胱癌患者。
结论
低级别膀胱癌和NMIBC与膀胱填塞较轻的临床进程相关。
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