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弥漫性大B细胞淋巴瘤监测PET/CT中意外出现的双心房18F-氟脱氧葡萄糖(18F-FDG)摄取。

Unanticipated Biatrial 18F-Fluorodeoxyglucose (18F-FDG) Uptake in Diffuse Large B-cell Lymphoma Surveillance PET/CT.

作者信息

Suthar Pokhraj P, Virmani Sumeet

机构信息

Department of Diagnostic Radiology and Nuclear Medicine, Rush University Medical Center, Chicago, USA.

出版信息

Cureus. 2024 Aug 18;16(8):e67120. doi: 10.7759/cureus.67120. eCollection 2024 Aug.

DOI:10.7759/cureus.67120
PMID:39290918
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11407483/
Abstract

Cardiac lymphomas are rare manifestations of diffuse large B-cell lymphoma (DLBCL), occurring either primarily or secondarily. Imaging modalities such as magnetic resonance/computed tomography (MR/CT) and fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) are pivotal for accurate detection and staging. However, cardiac FDG uptake during oncological PET/CT scans lacks specificity, necessitating further investigation into abnormal patterns, particularly in atrial FDG uptake, which may indicate underlying cardiac arrhythmias. A significant proportion of atrial fibrillation (AF) patients exhibit heightened FDG uptake in the atrium, correlating with an increased stroke risk. We present an asymptomatic 81-year-old female with DLBCL, hypertension, and AF, incidentally found to have abnormal biatrial FDG uptake on surveillance PET/CT. This case underscores the importance of comprehensive cardiology evaluation in asymptomatic oncology patients to manage potential cardiac complications effectively. Advanced imaging techniques and integrated care strategies are crucial for optimizing outcomes in cardiac lymphoma patients.

摘要

心脏淋巴瘤是弥漫性大B细胞淋巴瘤(DLBCL)的罕见表现,可原发或继发出现。磁共振成像/计算机断层扫描(MR/CT)和氟-18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG PET/CT)等影像学检查手段对于准确检测和分期至关重要。然而,肿瘤PET/CT扫描时心脏FDG摄取缺乏特异性,因此有必要进一步研究异常模式,尤其是心房FDG摄取,这可能提示潜在的心律失常。相当一部分心房颤动(AF)患者心房FDG摄取增加,这与中风风险增加相关。我们报告一例81岁无症状女性,患有DLBCL、高血压和AF,在监测PET/CT时偶然发现双心房FDG摄取异常。该病例强调了对无症状肿瘤患者进行全面心脏评估以有效管理潜在心脏并发症的重要性。先进的成像技术和综合护理策略对于优化心脏淋巴瘤患者的治疗效果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/227ab6991108/cureus-0016-00000067120-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/a9c129aac54c/cureus-0016-00000067120-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/d4fcd62ea64d/cureus-0016-00000067120-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/227ab6991108/cureus-0016-00000067120-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/a9c129aac54c/cureus-0016-00000067120-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/d4fcd62ea64d/cureus-0016-00000067120-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d944/11407483/227ab6991108/cureus-0016-00000067120-i03.jpg

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