Gaikwad Vidya, Patel Jay, Gaikwad Suhas, Aramandla Sneha, Phutane Rushikesh
Obstetrics and Gynaecology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University), Pune, IND.
Cureus. 2024 Aug 18;16(8):e67127. doi: 10.7759/cureus.67127. eCollection 2024 Aug.
Severe preeclampsia is a disorder of pregnancy, characterized by increased blood pressure (>140/90 mmHg) and proteinuria (≥ 300 mg/24 hours) at later than 20 weeks of gestation. Particularly in underdeveloped nations, severe preeclampsia and eclampsia have a significant negative impact on the health of expectant mothers, fetuses, and newborns. The HELLP (hemolysis, increased liver enzymes, low platelets) syndrome is thought to be a subset of preeclampsia, a group of hypertensive disorders of pregnancy that also includes eclampsia. Compared to preeclampsia alone, maternal and fetal problems are more severe in HELLP. There can be a diagnostic dilemma that arises when attempting to differentiate HELLP from its numerous imitators to determine the appropriate course of treatment. Here, we present a rare case of a pregnant woman presenting with preeclampsia complicated by manifestations and investigations suggestive of HELLP syndrome with acute kidney injury (AKI), retinal detachment, and symptoms of DIC (disseminated intravascular coagulation), which can be grievous to the mother as well as the fetus.
重度子痫前期是一种妊娠期疾病,其特征为妊娠20周后血压升高(>140/90 mmHg)和蛋白尿(≥300 mg/24小时)。特别是在欠发达国家,重度子痫前期和子痫对孕妇、胎儿和新生儿的健康有重大负面影响。HELLP(溶血、肝酶升高、血小板减少)综合征被认为是子痫前期的一个亚型,子痫前期是一组妊娠期高血压疾病,其中还包括子痫。与单纯子痫前期相比,HELLP患者的母婴问题更为严重。在试图将HELLP与其众多类似疾病区分开来以确定合适的治疗方案时,可能会出现诊断难题。在此,我们报告一例罕见病例,一名孕妇患有子痫前期,并伴有提示HELLP综合征的表现及检查结果,同时并发急性肾损伤、视网膜脱离和弥散性血管内凝血症状,这对母亲和胎儿都可能是严重的。