Li Shengyi, Hu Yue, Yang Lexin, Lv Baohua, Kong Xue, Qiang Guangliang
Internet of Things Engineering, Beijing-Dublin international College, Beijing University of Technology, Beijing, China.
China Academy of Chinese Medical Sciences, Guang'anmen Hospital, Beijing, China.
Front Bioeng Biotechnol. 2024 Sep 3;12:1454652. doi: 10.3389/fbioe.2024.1454652. eCollection 2024.
Pneumonia and tuberculosis are prevalent pulmonary diseases globally, each demanding specific care measures. However, distinguishing between these two conditions imposes challenges due to the high skill requirements for doctors, the impact of imaging positions and respiratory intensity of patients, and the associated high healthcare costs, emphasizing the imperative need for intelligent and efficient diagnostic methods.
This study aims to develop a highly accurate automatic diagnosis and classification method for various lung diseases (Normal, Pneumonia, and Tuberculosis). We propose a hybrid model, which is based on the InceptionV3 architecture, enhanced by introducing Deepwise Separable Convolution after the Inception modules and incorporating the Squeeze-and-Excitation mechanism. This architecture successfully enables the model to extract richer features without significantly increasing the parameter count and computational workload, thereby markedly improving the performance in predicting and classifying lung diseases. To objectively assess the proposed model, external testing and five-fold cross-validation were conducted. Additionally, widely used baseline models in the scholarly community were constructed for comparison.
In the external testing phase, the our model achieved an average accuracy (ACC) of 90.48% and an F1-score (F1) of 91.44%, which is an approximate 4% improvement over the best-performing baseline model, ResNet. In the five-fold cross-validation, our model's average ACC and F1 reached 88.27% ± 2.76% and 89.29% ± 2.69%, respectively, demonstrating exceptional predictive performance and stability. The results indicate that our model holds promise for deployment in clinical settings to assist in the diagnosis of lung diseases, potentially reducing misdiagnosis rates and patient losses.
Utilizing deep learning for automatic assistance in the diagnosis of pneumonia and tuberculosis holds clinical significance by enhancing diagnostic accuracy, reducing healthcare costs, enabling rapid screening and large-scale detection, and facilitating personalized treatment approaches, thereby contributing to widespread accessibility and improved healthcare services in the future.
肺炎和肺结核是全球常见的肺部疾病,每种疾病都需要特定的护理措施。然而,由于对医生的高技能要求、患者成像位置和呼吸强度的影响以及相关的高医疗成本,区分这两种疾病具有挑战性,这凸显了对智能高效诊断方法的迫切需求。
本研究旨在开发一种针对各种肺部疾病(正常、肺炎和肺结核)的高精度自动诊断和分类方法。我们提出了一种混合模型,该模型基于InceptionV3架构,通过在Inception模块之后引入深度可分离卷积并结合挤压激励机制进行增强。这种架构成功地使模型能够在不显著增加参数数量和计算工作量的情况下提取更丰富的特征,从而显著提高了肺部疾病预测和分类的性能。为了客观评估所提出的模型,进行了外部测试和五折交叉验证。此外,还构建了学术界广泛使用的基线模型进行比较。
在外部测试阶段,我们的模型平均准确率(ACC)达到90.48%,F1分数(F1)达到91.44%,比表现最佳的基线模型ResNet提高了约4%。在五折交叉验证中,我们模型的平均ACC和F1分别达到88.27%±2.76%和89.29%±2.69%,显示出卓越的预测性能和稳定性。结果表明,我们的模型有望在临床环境中部署,以协助肺部疾病的诊断,可能降低误诊率并减少患者损失。
利用深度学习自动辅助肺炎和肺结核的诊断具有临床意义,可提高诊断准确性、降低医疗成本、实现快速筛查和大规模检测,并促进个性化治疗方法,从而有助于未来广泛普及并改善医疗服务。