University of Health Sciences Turkey, Bakırköy Dr. Sadi Konuk Training and Research Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology - İstanbul, Turkey.
Kırıkhan State Hospital, Gynecology and Obstetrics Clinic - Antakya, Turkey.
Rev Assoc Med Bras (1992). 2024 Sep 16;70(9):e20240696. doi: 10.1590/1806-9282.20240696. eCollection 2024.
In endometrial cancer surgery, sentinel lymph node dissection is used instead of staging surgery, particularly in advanced disease that is limited to the uterus. The aim of this study is to evaluate our practice of robotic sentinel lymph node dissection, which is applied to endometrial cancer patients in our tertiary cancer treatment center, according to the current literature, and to share our own data.
Included in our analysis are patients who underwent robotic sentinel lymph node dissection for endometrial cancer utilizing indocyanine green in our center between January 2018 and January 2024.
In all, of the 93 endometrial carcinoma patients who underwent sentinel lymph node biopsy, 63 were classified as low-risk, while 30 were high-risk according to the European Society of Gynaecological Oncology and National Comprehensive Cancer Network guidelines. We found sentinel lymph nodes in both low-risk and high-risk patients, with an overall sensitivity of 96.32% (95% confidence interval [CI], 85.12-99.71), specificity of 100% (95%CI, 92.20-99.8), negative predictive value of 96.72% (95%CI, 87.03-99.89), and negative likelihood ratio of 0.06 (95%CI, 0.01-0.36).
After evaluating our data retrospectively, we determined that we were compatible with the current literature.
在子宫内膜癌手术中，采用前哨淋巴结清扫术替代分期手术，尤其是在局限于子宫的晚期疾病中。本研究旨在根据当前文献评估我们在三级癌症治疗中心对子宫内膜癌患者应用机器人前哨淋巴结清扫术的实践，并分享我们自己的数据。
我们的分析纳入了 2018 年 1 月至 2024 年 1 月期间在我们中心接受吲哚菁绿引导的机器人前哨淋巴结清扫术的子宫内膜癌患者。
在 93 例接受前哨淋巴结活检的子宫内膜癌患者中，根据欧洲妇科肿瘤学会和美国国家综合癌症网络指南，63 例患者为低危型，30 例患者为高危型。我们在低危和高危患者中均发现了前哨淋巴结，总体敏感性为 96.32%（95%置信区间，85.12-99.71），特异性为 100%（95%置信区间，92.20-99.8），阴性预测值为 96.72%（95%置信区间，87.03-99.89），阴性似然比为 0.06（95%置信区间，0.01-0.36）。
对我们的数据进行回顾性评估后，我们发现与当前文献一致。
