Duez J M, Freysz M, Kohli E, Minello C, Wilkening M, Kazmierczak A
Pathol Biol (Paris). 1985 May;33(5):440-3.
Quantitative bacteriologic monitoring of bronchial secretions obtained by protected distal catheterism was performed in 60 critically ill patients under mechanical ventilation. A number of factors which have significant bearing on bacterial growth in the respiratory tract were demonstrated. A statistical correlation was found between aspiration pneumonia and presence of Enterobacteriaceae, as well as between hospital-acquired pneumonia and recovery of opportunistic pathogens. S. aureus was especially prevalent in patients under corticosteroids. Aminoglycoside treatments increased the frequency of Acinetobacter infections, whereas prevalence of S. aureus and P. aeruginosa appeared unrelated to the use of any specific antibiotic. The value of bacteriology on protected distal catheter bronchoscopy specimens is to allow accurate diagnosis of lower respiratory tract infections and provide guidelines for the choice of appropriate antibiotics.
对60例机械通气的重症患者通过保护性远端导管插入术获取支气管分泌物进行定量细菌学监测。结果表明了一些对呼吸道细菌生长有重大影响的因素。发现吸入性肺炎与肠杆菌科细菌的存在之间以及医院获得性肺炎与机会性病原体的检出之间存在统计学相关性。金黄色葡萄球菌在接受皮质类固醇治疗的患者中尤为常见。氨基糖苷类药物治疗增加了不动杆菌感染的频率，而金黄色葡萄球菌和铜绿假单胞菌的患病率似乎与使用任何特定抗生素无关。对保护性远端导管支气管镜标本进行细菌学检测的价值在于能够准确诊断下呼吸道感染，并为选择合适的抗生素提供指导。
