Department of Anatomy, Faculty of Science, Mahidol University, Bangkok, Thailand.
Department of Radiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Surg Radiol Anat. 2024 Nov;46(11):1775-1781. doi: 10.1007/s00276-024-03484-w. Epub 2024 Sep 18.
The main purpose of this study was to investigate the dimensions of cerebral arteries in the Thai population using digital subtraction angiography (DSA), with a focus on the anterior cerebral artery (ACA), middle cerebral artery (MCA), and posterior cerebral artery (PCA). The research aimed to explore anatomical variations in diameters and lengths of these arteries across different sexes and age groups, which are crucial for cerebrovascular interventions.
This retrospective study measured the diameters and lengths of the ACA, MCA, and PCA in 177 Thai patients with an average age of 47.6 years (range: 11-82 years) with normal cerebral angiograms. Digital subtraction angiography (DSA) was used for the measurements.
The study found significant sex-based differences in the mean diameters of the left ACA (males: 2.12 ± 0.28 mm, females: 1.92 ± 0.20 mm; p < 0.01), right MCA (males: 2.50 ± 0.25 mm, females: 2.31 ± 0.17 mm; p < 0.01), and left MCA (males: 2.44 ± 0.19 mm, females: 2.30 ± 0.17 mm; p < 0.01) with males exhibiting larger diameters. The right ACA length was significantly longer in males (15.46 ± 1.74 mm) compared to females (13.98 ± 1.92 mm; p < 0.01). While no significant age-related differences were observed in diameters, a significant increase in length with age was noted for the left ACA in the ≥ 60 years group (13.61 ± 1.64 mm) compared to the < 60 years group (12.63 ± 1.36 mm; p < 0.01). Among others, significant correlations were found between the diameters of the left ACA and right MCA (r = 0.699; p < 0.01), and a strong correlation between left ACA length and left PCA diameter (r = 0.975; p < 0.01).
The findings provide invaluable data for tailoring neurosurgical approaches and designing angiographic equipment for the Thai population, emphasizing the importance of considering anatomical variations in clinical practice. These results highlight the necessity for personalized medical care based on anatomical differences to improve cerebrovascular intervention outcomes.
本研究旨在通过数字减影血管造影（DSA）研究泰国人群的大脑动脉的维度，重点关注大脑前动脉（ACA）、大脑中动脉（MCA）和大脑后动脉（PCA）。研究目的是探索不同性别和年龄组这些动脉的直径和长度的解剖学变化，这对于脑血管介入至关重要。
这项回顾性研究对 177 名平均年龄为 47.6 岁（范围：11-82 岁）的泰国患者进行了数字减影血管造影（DSA）检查，这些患者的脑血管造影正常。测量了 ACA、MCA 和 PCA 的直径和长度。
研究发现，左 ACA（男性：2.12 ± 0.28mm，女性：1.92 ± 0.20mm；p<0.01）、右 MCA（男性：2.50 ± 0.25mm，女性：2.31 ± 0.17mm；p<0.01）和左 MCA（男性：2.44 ± 0.19mm，女性：2.30 ± 0.17mm；p<0.01）的平均直径存在显著的性别差异，男性的直径较大。男性右 ACA 长度（15.46 ± 1.74mm）明显长于女性（13.98 ± 1.92mm；p<0.01）。虽然直径没有明显的年龄相关性差异，但≥60 岁组的左 ACA 长度（13.61 ± 1.64mm）明显大于<60 岁组（12.63 ± 1.36mm；p<0.01）。此外，还发现左 ACA 直径与右 MCA 直径之间存在显著相关性（r=0.699；p<0.01），左 ACA 长度与左 PCA 直径之间存在强相关性（r=0.975；p<0.01）。
研究结果为制定适合泰国人群的神经外科手术方法和设计血管造影设备提供了宝贵的数据，强调了在临床实践中考虑解剖学差异的重要性。这些结果强调了基于解剖学差异的个性化医疗护理的必要性，以改善脑血管介入治疗的结果。
