Hung Kan-Lin, Lu Yong, Tian Yinglun, Xue Shilin, Gao Guodong, Gao Qiyue, Xu Nanfang, Wang Shenglin
Department of Orthopaedics, Peking University Third Hospital, Beijing, People's Republic of China.
Engineering Research Center of Bone and Joint Precision Medicine, Beijing, People's Republic of China.
J Bone Joint Surg Am. 2024 Dec 4;106(23):2215-2222. doi: 10.2106/JBJS.23.01464. Epub 2024 Sep 18.
Conventional surgical procedures for atlantoaxial instability or dislocation (AAI/D) have been associated with a high prevalence of postoperative occipitocervical pain and dysfunction, as well as substantial perioperative blood loss. We hypothesized that minimally invasive surgery for posterior atlantoaxial lateral mass joint fusion (MIS-PALF), a procedure that can largely avoid disruption of suboccipital musculature, would be superior to the standard Goel-Harms technique in terms of postoperative pain and perioperative blood loss.
This was a prospective cohort study of patients undergoing MIS-PALF for AAI/D at Peking University Third Hospital's Department of Orthopaedics from January 2021 to December 2021 and a historical control group of patients with the same diagnoses who were treated with the Goel-Harms technique. The duration of surgery, perioperative blood loss, postoperative length of hospital stay, postoperative body temperature, pain, supplementary use of narcotics, spinal cord function/improvement (assessed using the Japanese Orthopaedic Association [JOA] scores), reduction of AAI/D (determined based on radiographic parameters), rate of successful fusion, and complication rate were all compared between the 2 groups.
No significant differences were noted between the groups (43 MIS-PALF cases, 86 control cases) regarding baseline data, operative time, spinal cord function or improvement, reduction of AAI/D, rate of successful fusion, and complication rate. MIS-PALF was associated with significantly less perioperative blood loss, a shorter postoperative hospital stay (decreased by 30.8%), lower intensity and frequency of postoperative pain (decreased by 10.6% and 61.9%, respectively), less need for supplementary narcotics, and less frequent postoperative fever (decreased by 48.7%).
This was the first prospective cohort study of which we are aware on minimally invasive procedures for atlantoaxial fusion. Clinical efficacy (AAI/D reduction, rate of successful atlantoaxial fusion, JOA score improvement), efficiency (operative time), and safety (complications) of MIS-PALF appeared to be noninferior to those of the Goel-Harms technique. MIS-PALF was superior in terms of postoperative occipitocervical pain and length of hospital stay, both of which directly affect overall patient satisfaction and postoperative recovery of quality of life.
Therapeutic Level II . See Instructions for Authors for a complete description of levels of evidence.
寰枢椎不稳或脱位(AAI/D)的传统外科手术与术后枕颈部疼痛和功能障碍的高发生率以及围手术期大量失血有关。我们假设,后路寰枢椎外侧块关节融合微创手术(MIS-PALF),一种可在很大程度上避免枕下肌肉组织破坏的手术,在术后疼痛和围手术期失血方面优于标准的戈尔-哈姆斯技术。
这是一项前瞻性队列研究,研究对象为2021年1月至2021年12月在北京大学第三医院骨科接受MIS-PALF治疗AAI/D的患者,以及一组采用戈尔-哈姆斯技术治疗的相同诊断的历史对照组患者。比较两组患者的手术时间、围手术期失血量、术后住院时间、术后体温、疼痛程度、麻醉剂补充使用情况、脊髓功能/改善情况(采用日本骨科协会[JOA]评分评估)、AAI/D的复位情况(根据影像学参数确定)、融合成功率和并发症发生率。
两组(43例MIS-PALF病例,86例对照病例)在基线数据、手术时间、脊髓功能或改善情况、AAI/D复位情况、融合成功率和并发症发生率方面未发现显著差异。MIS-PALF的围手术期失血量明显减少,术后住院时间缩短(减少30.8%),术后疼痛强度和频率降低(分别降低10.6%和61.9%),麻醉剂补充需求减少,术后发热频率降低(减少48.7%)。
这是我们所知的第一项关于寰枢椎融合微创手术的前瞻性队列研究。MIS-PALF的临床疗效(AAI/D复位、寰枢椎融合成功率、JOA评分改善)、效率(手术时间)和安全性(并发症)似乎不劣于戈尔-哈姆斯技术。MIS-PALF在术后枕颈部疼痛和住院时间方面更具优势,这两者都直接影响患者的总体满意度和术后生活质量的恢复。
治疗性II级。有关证据水平的完整描述,请参阅作者指南。