School of Veterinary Medicine and Science, University of Nottingham, Sutton Bonington, United Kingdom..
Haiken Laboratory, Concepcion, Chile.
Res Vet Sci. 2024 Nov;180:105403. doi: 10.1016/j.rvsc.2024.105403. Epub 2024 Sep 5.
Feline Leukemia Virus is a retrovirus causing fatal disease in domestic cats. While FeLV has been controlled in many countries, it remains a major concern in Latin American countries. This study conducted an epidemiological survey of FeLV in 182 Chilean domestic cats using PCR to detect provirus infection. The results were analysed using Multivariate Logistic Regression to examine risk factors associated with FeLV detection. The FeLV prevalence was 54.95 %, and statistically significant associations (p < 0.05) were found for two protective factors and one risk factor. Cats from Concepcion city (95 %CI 0.08-0.56 %) and cats sampled in 2022 (95 %CI 0.1-0.06 %) had lower odds ratios for provirus positivity, whereas non-vaccinated cats (95 %CI 2.3-15.8 %) had an increased odds ratio. No other factors were statistically significant. The high FeLV prevalence is similar to other Latin American countries and the geographical differences highlighted in this study likely correspond to the socioeconomic status of the owners. This study highlights the need for improved FeLV control measures such as promoting FeLV vaccination, implementing health screening prior to adoption of new cats, and educating owners about FeLV to control its circulation.
猫白血病病毒是一种逆转录病毒，可导致家猫致命疾病。虽然在许多国家已经控制了 FeLV，但它仍然是拉丁美洲国家的主要关注点。本研究使用 PCR 对 182 只智利家猫中的 FeLV 进行了流行病学调查，以检测前病毒感染。使用多变量逻辑回归分析结果，以检查与 FeLV 检测相关的风险因素。FeLV 的患病率为 54.95%，两个保护因素和一个风险因素与统计学显著相关（p<0.05）。来自康塞普西翁市的猫（95%CI 0.08-0.56%）和 2022 年采样的猫（95%CI 0.1-0.06%）的前病毒阳性率比值较低，而未接种疫苗的猫（95%CI 2.3-15.8%）的比值则较高。其他因素没有统计学意义。高 FeLV 患病率与其他拉丁美洲国家相似，本研究中强调的地理差异可能与主人的社会经济地位相对应。本研究强调需要采取改进的 FeLV 控制措施，例如推广 FeLV 疫苗接种、在新猫被收养前进行健康筛查，并对猫主人进行 FeLV 教育以控制其传播。
