Laboratório de Patologia Animal (LAPA), Centro de Ciências Agroveterinárias - Universidade do Estado de Santa Catarina (CAV/UDESC), Lages, SC, Brazil.
Médica veterinária autônoma, Lages, SC, Brazil.
Comp Immunol Microbiol Infect Dis. 2024 Sep;112:102228. doi: 10.1016/j.cimid.2024.102228. Epub 2024 Aug 13.
The objective of this study was to categorise diseases associated with FeLV infection in cats. A total of 154 cats were submitted to necropsy, histopathology exam and anti-FeLV immunohistochemistry (IHC), and 83 (50.9 %) were IHC FeLV-positive. The cats age means of 4.1 years, including 3.6 % kittens, 34.9 % junior, 37.4 % prime, 18.1 % mature, 2.4 % senior, 3.6 % unknown age. Neoplastic diseases were most prevalent with leukaemia and lymphoma being most predominant, followed by viral diseases, bacterial, trauma, degenerative, intoxications, parasitic, malformation and others. FeLV+ cats were 5.73 times more likely to be diagnosed with neoplasms than other diseases. The odds ratio (OR) of FeLV+ cats developing leukaemia (OR = 7.75) and lymphoma (OR = 6.75) was higher than other neoplasms. FeLV infection was more prevalent in the mixed breed, junior to prime, male, with neoplastic diseases, including leukaemia and lymphoma. Therefore, understanding the diseases associated with FeLV is of paramount importance in Brazil due to its high prevalence, and it may encourage the implementation of prophylactic measures to reduce its dissemination.
本研究旨在对猫科动物 FeLV 感染相关疾病进行分类。共有 154 只猫接受了尸检、组织病理学检查和抗 FeLV 免疫组织化学（IHC）检查，其中 83 只（50.9%）IHC FeLV 阳性。这些猫的平均年龄为 4.1 岁，包括 3.6%的幼猫、34.9%的幼年期猫、37.4%的成年期猫、18.1%的成熟猫、2.4%的老年猫和 3.6%的未知年龄猫。肿瘤性疾病最为常见，以白血病和淋巴瘤最为常见，其次是病毒性疾病、细菌性疾病、创伤性疾病、退行性疾病、中毒性疾病、寄生虫性疾病、畸形性疾病和其他疾病。FeLV+猫患肿瘤的可能性是其他疾病的 5.73 倍。FeLV+猫患白血病（OR=7.75）和淋巴瘤（OR=6.75）的几率高于其他肿瘤。混合品种、幼年期到成年期、雄性猫的 FeLV 感染更为普遍，且常伴有肿瘤性疾病，包括白血病和淋巴瘤。因此，了解与 FeLV 相关的疾病在巴西非常重要，因为其患病率较高，这可能会鼓励实施预防措施来减少其传播。
