Dadzie Mary-Ann, Yarney Joel, Nyantakyi Andrew Yaw, Tackie Judith Naa Odey
National Centre for Radiotherapy and Nuclear Medicine, Korle Bu Teaching Hospital, P.O Box KB 369, Accra, Ghana.
Transl Oncol. 2024 Dec;50:102124. doi: 10.1016/j.tranon.2024.102124. Epub 2024 Sep 17.
We report a case of alveolar rhabdomyosarcoma of the infratemporal region in a female child. An 8year old female was diagnosed with alveolar rhabdomyosarcoma 10 years ago. A computed tomography (CT) scan showed large mass in the right pterygopalatine fossa extending into the buccal, masticator and parapharyngeal spaces with involvement of the pterygoid and masseter muscles. Several multidisciplinary discussions were held concerning the case to determine the best treatment strategy. Child received neoadjuvant chemotherapy followed by radiotherapy. Six months post radiotherapy, CT scan reported a residual lesion for which multiple biopsies showed no residual tumor. Patient is doing well 10 years after treatment with no evidence of recurrence, Notably, this was the first case discussed at the inception of the pediatric multidisciplinary tumor board.
我们报告了一例女童颞下区肺泡状横纹肌肉瘤的病例。一名8岁女童于10年前被诊断为肺泡状横纹肌肉瘤。计算机断层扫描（CT）显示右翼腭窝有一个大肿块，延伸至颊间隙、咀嚼肌间隙和咽旁间隙，翼状肌和咬肌受累。针对该病例进行了多次多学科讨论，以确定最佳治疗策略。患儿接受了新辅助化疗，随后进行了放疗。放疗后6个月，CT扫描显示有残留病变，多次活检均未发现残留肿瘤。治疗10年后，患者情况良好，无复发迹象。值得注意的是，这是儿科多学科肿瘤委员会成立之初讨论的首例病例。
