Thrall D E, Dewhirst M W
Vet Clin North Am Small Anim Pract. 1985 Jul;15(4):835-43. doi: 10.1016/s0195-5616(85)50040-6.
Radiation alone can be used to treat mast cell tumors that are not likely to metastasize (that is, differentiated or localized lymphorecticular tumors). In patients with mast cell tumors that are likely to metastasize (that is, undifferentiated, metastatic mast cell disease or generalized lymphoreticular neoplasms), radiation should not be used as the only treatment agent. In these patients, treatment combinations of hyperthermia/chemotherapy and radiation/hyperthermia/chemotherapy have been shown to have promise, but these treatment combinations need to be evaluated in prospective trials.
单独放疗可用于治疗不太可能发生转移的肥大细胞瘤(即分化型或局限性淋巴网状细胞瘤)。对于可能发生转移的肥大细胞瘤患者(即未分化的、转移性肥大细胞病或全身性淋巴网状肿瘤),放疗不应作为唯一的治疗手段。在这些患者中,热疗/化疗以及放疗/热疗/化疗的联合治疗已显示出前景,但这些联合治疗需要在前瞻性试验中进行评估。