1-去氨基-8-D-精氨酸加压素与冷沉淀在血管性血友病变异型中的应用

1-Deamino-8-D-arginine vasopressin and cryoprecipitate in variant von Willebrand disease.

作者信息

Hanna W T, Slywka J, Dent J, Ruggeri Z M, Zimmerman T S

出版信息

Am J Hematol. 1985 Oct;20(2):169-73. doi: 10.1002/ajh.2830200210.

DOI:10.1002/ajh.2830200210

Abstract

The effect of infusing DDAVP and cryoprecipitate either singly or in combination was studied in a patient with variant von Willebrand disease. Both DDAVP and cryoprecipitate caused only partial correction in the hemostatic defect when used as a single agent. A combination of DDAVP and cryoprecipitate induced a complete correction of the hemostatic defect as well as factor VIII related properties.

摘要

在一名血管性血友病变异型患者中，研究了单独输注去氨加压素（DDAVP）和冷沉淀或两者联合输注的效果。单独使用时，DDAVP和冷沉淀仅能部分纠正止血缺陷。DDAVP与冷沉淀联合使用可完全纠正止血缺陷以及与因子VIII相关的特性。