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感染HIV且心血管风险为低/中度至高度人群中他汀类药物处方的性别差异

Gender Disparities in Statin Prescriptions in People With HIV With Low/Moderate to High Cardiovascular Risk.

作者信息

Abela Irene A, Chammartin Frédérique, Amstutz Alain, Surial Bernard, Ballif Marie, Marzolini Catia, Aebi-Popp Karoline, Notter Julia, Segeral Olivier, Stoeckle Marcel, Cavassini Matthias, Bernasconi Enos, Günthard Huldrych F, Kouyos Roger D, Pasin Chloé

机构信息

Department of Infectious Diseases and Hospital Epidemiology, University Hospital Zurich, Zurich, Switzerland.

Institute of Medical Virology, University of Zurich, Zurich, Switzerland.

出版信息

Open Forum Infect Dis. 2024 Sep 9;11(9):ofae502. doi: 10.1093/ofid/ofae502. eCollection 2024 Sep.

DOI:10.1093/ofid/ofae502
PMID:39296341
原文链接:
https://pmc.ncbi.nlm.nih.gov/articles/PMC11409876/
Abstract

The REPRIEVE trial suggests that primary cardiovascular disease (CVD) prevention could be considered among people with HIV at low CVD risk. We found cisgender women with low/moderate and high CVD risk are less likely to receive statins than cisgender men. Efforts are needed to guarantee equal access to statin-based CVD prevention.

摘要

“缓解”试验表明,对于心血管疾病(CVD)低风险的HIV感染者,可考虑进行原发性心血管疾病预防。我们发现,心血管疾病低/中度风险和高风险的顺性别女性比顺性别男性接受他汀类药物治疗的可能性更小。需要努力确保在基于他汀类药物的心血管疾病预防方面获得平等的机会。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c45/11409876/de6dcce384c2/ofae502f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c45/11409876/de6dcce384c2/ofae502f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1c45/11409876/de6dcce384c2/ofae502f1.jpg

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N Engl J Med. 2023 Aug 24;389(8):687-699. doi: 10.1056/NEJMoa2304146. Epub 2023 Jul 23.
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Assessment of Sex Disparities in Nonacceptance of Statin Therapy and Low-Density Lipoprotein Cholesterol Levels Among Patients at High Cardiovascular Risk.
评估高心血管风险患者中他汀类药物治疗不接受率和低密度脂蛋白胆固醇水平的性别差异。
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Sex and Gender Bias as a Mechanistic Determinant of Cardiovascular Disease Outcomes.作为心血管疾病结局机制决定因素的性别与性别的偏差
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Disparities in the Prescription of Statins in the Primary Care Setting: A Retrospective Observational Study.初级保健环境中他汀类药物处方的差异:一项回顾性观察研究。
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