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[二尖瓣脱垂。电生理研究结果]

[Mitral valve prolapse. Results of electrophysiological studies].

作者信息

Perrot B, Danchin N, Preiss M A, Bara P, Cherrier F, Faivre G

出版信息

Arch Mal Coeur Vaiss. 1985 Jul;78(7):1001-8.

PMID:3929728
Abstract

Classically, the frequency of latent left-sided Kent bundles and ventricular tachycardia (VT) is increased in mitral valve prolapse (MVP). To verify this hypothesis, 23 patients with clinical and echocardiographic (M mode and 2D) signs of MVP underwent electrophysiological studies for dizziness or syncope (12 cases) or palpitations (11 cases). In addition to the standard electrophysiological studies, analysis of sinoatrial and atrioventricular conduction, they underwent programmed ventricular pacing (St V2): coupled and then paired St V2 in sinus rhythm and during ventricular pacing (100-150/min) under basal conditions (15 patients), after injection of 2 mg Atropine (6 patients), and 10 micrograms of Isoproterenol (4 patients). These manoeuvres showed that symptoms of dizziness were due to increased vagal tone in 6 cases (associated with paroxysmal nodal tachycardia--PNT--in 3 cases), to sinoatrial block in 2 cases (associated with atrial tachycardia in 1 case), to suprahisian conduction defects in 3 cases (associated with atrial tachycardia in 1 case) and to VT in 1 case. Palpitations were due to VT in 1 case, atrial tachycardia in 1 case and PNT in 9 cases. Our analysis showed a high incidence of PNT (10 cases) with normal inter critical ECG. These arrhythmias were due to intranodal reentry in 7 cases (70%), to a latent left-sided Kent bundle in 2 cases and to a paraseptal Kent bundle in 1 case. These PNT were characterised by induction during exercise (6 cases) and by their association with flutter-type reentry (5 cases).(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

传统上认为,二尖瓣脱垂(MVP)时左侧隐匿性肯特束及室性心动过速(VT)的发生率会增加。为验证这一假说,对23例有MVP临床及超声心动图(M型和二维)表现的患者进行了电生理研究,这些患者因头晕或晕厥(12例)或心悸(11例)就诊。除了进行标准的电生理研究、分析窦房结和房室传导外,他们还接受了程控心室起搏(St V2):在基础状态下(15例患者)、注射2毫克阿托品后(6例患者)以及注射10微克异丙肾上腺素后(4例患者),于窦性心律及心室起搏时(100 - 150次/分钟)进行耦合及随后的配对St V2。这些操作显示,6例患者的头晕症状是由于迷走神经张力增加(3例伴有阵发性结性心动过速——PNT),2例是由于窦房阻滞(1例伴有房性心动过速),3例是由于希氏束以上传导缺陷(1例伴有房性心动过速),1例是由于VT。心悸的原因是1例VT、1例房性心动过速和9例PNT。我们的分析显示,临界间期心电图正常时PNT的发生率很高(10例)。这些心律失常中,7例(70%)是由于结内折返,2例是由于左侧隐匿性肯特束,1例是由于间隔旁肯特束。这些PNT的特点是运动时可诱发(6例)以及与扑动型折返相关(5例)。(摘要截选至250字)

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