Clary C, Jacob C, Blaive B, Kermarec J
Ann Pathol. 1985;5(2):107-14.
Intravascular bronchiolo-alveolar tumor (IVBAT) is a rare pulmonary neoplasm of assumed endothelial nature. We report a new case of peculiar interest because of the association of a diffuse pulmonary involvement with multiple visceral localisations, which has scarcely been proved during life. We found out a striking endothelial differentiation on microscopic examination. The presence of F VIII RAg in many tumor cells as well as the ultramicroscopic findings support the endothelial differentiation. Thus, we regard our case of IVBAT as an aggressive form of the disease behaving as a real angiosarcoma.
血管内细支气管肺泡瘤（IVBAT）是一种罕见的、推测具有内皮性质的肺肿瘤。我们报告了一例新的、特别有趣的病例，因为其存在弥漫性肺受累并伴有多个内脏部位受累，而这在生前很少得到证实。我们在显微镜检查中发现了显著的内皮分化。许多肿瘤细胞中存在F VIII RAg以及超微结构检查结果均支持内皮分化。因此，我们认为我们所报道的IVBAT病例是该疾病的一种侵袭性形式，表现为真正的血管肉瘤。
