Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, M3J1P3, ON, Canada.
Math Biosci. 2024 Nov;377:109303. doi: 10.1016/j.mbs.2024.109303. Epub 2024 Sep 17.
Vaping, or the use of electronic cigarettes (e-cigarettes), is an ongoing issue for public health. The rapid increase in e-cigarette usage, particularly among adolescents, has often been referred to as an epidemic. Drawing upon this epidemiological analogy between vaping and infectious diseases as a theoretical framework, we present a deterministic compartmental model of adolescent e-cigarette smoking which accounts for social influences on initiation, relapse, and cessation behaviours. We use results from a sensitivity analysis of the model's parameters on various response variables to identify key influences on system dynamics and simplify the model into one that can be analysed more thoroughly. We identify a single feasible endemic equilibrium for the proportion of smokers that decreases as social influence on cessation increases. Through steady state and stability analyses, as well as simulations of the model, we conclude that social influences from and on temporary quitters are not important in overall model dynamics, and that social influences from permanent quitters can have a significant impact on long-term system dynamics. In particular, we show that social influence on cessation can induce persistent recurrent smoking outbreaks.
vaping,或使用电子烟(电子烟),是一个持续存在的公共卫生问题。电子烟使用率的迅速增加,尤其是在青少年中,通常被称为一种流行病。借鉴这一流行病类比,即 vaping 和传染病之间的理论框架,我们提出了一个青少年电子烟吸烟的确定性房室模型,该模型考虑了对起始、复发和戒烟行为的社会影响。我们使用对模型参数对各种响应变量的敏感性分析的结果来确定对系统动态的关键影响,并将模型简化为一个可以更彻底分析的模型。我们确定了一个可行的、吸烟者比例的地方病平衡点,随着戒烟对社会影响的增加而降低。通过稳态和稳定性分析,以及对模型的模拟,我们得出结论,来自和对临时戒烟者的社会影响在整体模型动态中并不重要,而来自永久性戒烟者的社会影响可能对长期系统动态产生重大影响。特别是,我们表明,对戒烟的社会影响可以引起持续的反复吸烟爆发。