Department of Oral & Maxillofacial Pathology and Microbiology, Sharad Pawar Dental College & Hospital, Datta Meghe Institute of Higher Education and Research, Sawangi (Meghe), Wardha, 442004, Maharashtra, India.
BMC Oral Health. 2024 Sep 19;24(1):1119. doi: 10.1186/s12903-024-04894-3.
Fibrous dysplasia (FD) is a benign fibro-osseous lesion, a skeletal developmental anomaly of the bone-forming mesenchyme. The diagnosis of fibro-osseous lesions, particularly those of the jaw bones, poses significant challenges to clinicians and pathologists since it requires a correlation of clinical, radiological, histological, and surgical findings. Accurate and specific diagnosis is crucial as treatment modalities differ with different fibro-osseous lesions.
This retrospective analysis presents a case series of a rare condition of monostotic FD in the maxillofacial region affecting jaw bones diagnosed and/or treated over period of 10 years.
Five cases of monostotic FD were diagnosed and treated between a period of 2013 and 2023. The cases from the 2nd to 8th decade were included in the analysis with equal involvement of males and females. Out of five cases, four cases were involving maxilla and 1 showed involvement of mandible.
FD is a rare entity affecting the jaw bones which often lead to disfigurement of face. Early detection is warranted to decrease potential complications. In addition, genetic analysis could help in understanding the occurrence in certain population.
纤维结构不良（FD）是一种良性纤维骨性病变，是成骨间充质的骨骼发育异常。纤维骨性病变的诊断，特别是颌骨的纤维骨性病变，对临床医生和病理学家提出了重大挑战，因为它需要将临床、影像学、组织学和手术发现进行关联。准确和具体的诊断至关重要，因为不同的纤维骨性病变需要不同的治疗方法。
本回顾性分析报告了 10 年来在颌面区域诊断和/或治疗的一种罕见的单骨性 FD 病例系列。
在 2013 年至 2023 年期间诊断和治疗了 5 例单骨性 FD。纳入了第 2 至 8 个十年的病例，男女比例相等。5 例中，4 例累及上颌骨，1 例累及下颌骨。
FD 是一种罕见的颌骨病变，常导致面部畸形。早期发现有助于减少潜在的并发症。此外，遗传分析有助于了解某些人群中的发病情况。
