基于在线正念减压改善宫颈癌患者癌因性疲乏及疾病相关心理变量的研究：一项随机对照试验。
A study on improving cancer-related fatigue and disease-related psychological variables in patients with cervical cancer based on online mindfulness-based stress reduction: a randomized controlled trial.
机构信息
Department of Social Medicine, School of Health Management, China Medical University, No. 77 PuHe Road, Shenyang North New Area, Shenyang, 110122, China.
Department of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang, 110004, China.
出版信息
BMC Womens Health. 2024 Sep 19;24(1):525. doi: 10.1186/s12905-024-03368-6.
BACKGROUND
The persistent destructive power of cancer-related fatigue (CRF) has been regarded as the biggest influencing factor affecting the postoperative physical and mental health of patients with cervical cancer. During this process, patients might also experience different feelings of disease-related psychological. Therefore, this study aimed to adopt mindfulness-based stress reduction (MBSR) to intervene in patients with cervical cancer, and conducted follow-up for 3 and 6 months to observe the effects of changes in CRF, uncertainty in illness, coping styles, sense of coherence (SOC), and perceived social support (PSS).
METHODS
A randomized controlled trial was conducted in ShengJing Hospital of China Medical University. A total of 102 patients were selected, and 78 patients completed the whole process, including 40 in the experimental group and 38 in the control group. Data were collected according to Cancer Fatigue Scale, Medical Coping Modes Questionnaire, Multidimensional Scale of Perceived Social Support, and Sense of Coherence-13. The change trend and difference of the two groups of research data were compared by repeated measurement analysis of variance. Bonferroni test was used for multiple tests between groups.
RESULTS
The CRF, SOC, and coping styles of the MBSR group showed a decreasing trend (P < 0.001) at after MBSR, 3 months follow-up, and 6 months follow-up compared to the before MBSR. However, the uncertainty in illness of the MBSR group showed a decreasing trend (P < 0.001) at after MBSR compared to the before MBSR, and it rose in 3 months follow-up and 6 months follow-up.
CONCLUSION
MBSR can effectively alleviate the fatigue of CRF after treatment, while improving their psychological environment. Medical workers can consider implementing online MBSR for patients with cervical cancer in their daily rehabilitation nursing, which is beneficial for their recovery.
TRIAL REGISTRATION
China Clinical Trial Registration Center ChiCTR2000040122 (https//www.chictr.org.cn/). Registered on November 21, 2020.
背景
癌症相关疲劳（CRF）的持续破坏力被认为是影响宫颈癌患者术后身心健康的最大影响因素。在此过程中，患者可能还会经历与疾病相关的不同心理感受。因此，本研究旨在采用正念减压（MBSR）对宫颈癌患者进行干预，并进行 3 个月和 6 个月的随访，观察 CRF、疾病不确定性、应对方式、心理一致感（SOC）和感知社会支持（PSS）变化的效果。
方法
在中国医科大学盛京医院进行随机对照试验。共纳入 102 例患者，78 例患者完成全过程，其中实验组 40 例，对照组 38 例。根据癌症疲劳量表、医学应对方式问卷、多维感知社会支持量表和心理一致感 13 项进行数据收集。采用重复测量方差分析比较两组研究数据的变化趋势和差异，组间多重检验采用 Bonferroni 检验。
结果
MBSR 组的 CRF、SOC 和应对方式在 MBSR 后、3 个月随访和 6 个月随访时呈下降趋势（P<0.001），而 MBSR 组的疾病不确定性在 MBSR 后呈下降趋势（P<0.001），但在 3 个月随访和 6 个月随访时呈上升趋势。
结论
MBSR 能有效缓解宫颈癌患者治疗后 CRF，同时改善其心理环境。医务人员在日常康复护理中可考虑为宫颈癌患者实施在线 MBSR，有利于其康复。
试验注册
中国临床试验注册中心 ChiCTR2000040122（https//www.chictr.org.cn/）。于 2020 年 11 月 21 日注册。
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