关于可植入式避孕器的事实：世界卫生组织会议纪要
Facts about an implantable contraceptive: memorandum from a WHO meeting.
出版信息
Bull World Health Organ. 1985;63(3):485-94.
Abstract
This Memorandum reviews the results of research undertaken in animals and human subjects on the implantable contraceptive, Norplant, and where relevant, its components, levonorgestrel and Silastic. Results from clinical trials, including effectiveness and side-effects, are evaluated and service delivery aspects commented on. The Memorandum concludes with a statement regarding the use of Norplant as an option for long-term reversible contraception.
摘要
本备忘录回顾了在动物和人类受试者身上对可植入式避孕药Norplant及其相关成分左炔诺孕酮和硅橡胶进行的研究结果。对临床试验结果，包括有效性和副作用进行了评估，并对服务提供方面进行了评论。备忘录最后就使用Norplant作为长期可逆避孕方法的选择发表了声明。
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本文引用的文献
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THE USE OF SILICONE RUBBER AS A CARRIER FOR PROLONGED DRUG THERAPY.硅橡胶作为长期药物治疗载体的应用。
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Pharmacokinetic and pharmacodynamic investigations with vaginal devices releasing levonorgestrel at a constant, near zero order rate.对以恒定、接近零级速率释放左炔诺孕酮的阴道给药装置进行的药代动力学和药效学研究。
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Plasma levels of levonorgestrel in women during longterm use of norplant.长期使用左炔诺孕酮皮下埋植剂的女性体内左炔诺孕酮的血浆水平。
Contraception. 1981 Feb;23(2):197-209. doi: 10.1016/0010-7824(81)90105-0.
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Menstrual blood loss with contraceptive subdermal levonorgestrel implants.含左炔诺孕酮皮下植入剂的避孕药具的月经失血情况。
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Effect of levonorgestrel contraceptive implants, Norplant, on blood coagulation.左炔诺孕酮避孕植入剂（诺普兰）对血液凝固的影响。
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Effect of subdermal levonorgestrel contraceptive implants, Norplant, on serum lipids.皮下植入左炔诺孕酮避孕剂（Norplant）对血脂的影响。
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10
Effect of subdermal levonorgestrel contraceptive implants, Norplant, on liver functions.皮下植入左炔诺孕酮避孕剂（Norplant）对肝功能的影响。
Contraception. 1984 Nov;30(5):407-12. doi: 10.1016/0010-7824(84)90032-5.
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