Department of Physical Education and Sports, Faculty of Sport Sciences, Sport and Health University Research Institute (iMUDS), University of Granada, Granada, Spain.
Department of Health Sciences, Institute for Innovation & Sustainable Food Chain Development, Public University of Navarre, Pamplona, Spain.
Am J Hum Biol. 2024 Nov;36(11):e24157. doi: 10.1002/ajhb.24157. Epub 2024 Sep 20.
This study aims to examine the relationship between resting vagal-related heart rate variability (HRV) parameters and heart rate (HR) with resting metabolic rate (RMR) and respiratory exchange ratio (RER) in young adults.
A total of 74 young adults (22 ± 2 years old, 51 women) were included in this cross-sectional study. HRV was assessed using a HR monitor, whereas RMR and RER were determined by indirect calorimetry.
Linear regression analyses showed a positive association between HR and RER in women (standardized β = 0.384, p = 0.008), while negative associations were observed between vagal-related HRV parameters and RER in women (β ranged from -0.262 to -0.254, all p ≤ 0.042). No significant association was found between the abovementioned physiological parameters in men.
Here, we show that HR is positively associated with RER in young women but not in men, while vagal-related HRV parameters are inversely related to RMR, therefore suggesting a potential sexual dimorphism between cardiac rhythm and its relationship with markers of cardiometabolic health status.
ClinicalTrials.gov identifier: NCT02365129.
本研究旨在探讨年轻成年人静息迷走神经相关心率变异性（HRV）参数与心率（HR）与静息代谢率（RMR）和呼吸交换率（RER）之间的关系。
本横断面研究共纳入 74 名年轻成年人（22±2 岁，51 名女性）。使用 HR 监测仪评估 HRV，通过间接量热法测定 RMR 和 RER。
线性回归分析显示，女性 HR 与 RER 呈正相关（标准化β=0.384，p=0.008），而女性迷走神经相关 HRV 参数与 RER 呈负相关（β范围从-0.262 到-0.254，均 p≤0.042）。男性上述生理参数之间未发现显著相关性。
本研究表明，女性 HR 与 RER 呈正相关，但男性则无此相关性，而迷走神经相关 HRV 参数与 RMR 呈负相关，这提示心脏节律及其与心脏代谢健康状况标志物之间的关系存在潜在的性别二态性。
ClinicalTrials.gov 标识符：NCT02365129。
