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慢性失眠症患者局部一致性的静态和时间动态改变:一项静息态功能磁共振成像研究

Static and temporal dynamic alterations of regional homogeneity in chronic insomnia: a resting-state fMRI study.

作者信息

Chen Xiaoxin, Zhang Wenzheng, Wang Maoyang, Li Jun

机构信息

Department of Radiology, Yantai Affiliated Hospital of Binzhou Medical University, Yantai, China.

出版信息

Sleep Biol Rhythms. 2024 Jul 2;22(4):541-544. doi: 10.1007/s41105-024-00541-0. eCollection 2024 Oct.

Abstract

UNLABELLED

To explore brain function alterations in chronic insomnia (CI). 65 CI patients and 48 healthy controls were included to analyze abnormal alterations in brain spontaneous activity using static regional homogeneity (sReHo) and dynamic regional homogeneity (dReHo) methods. CI patients focused on decreased sReHo in bilateral lingual gyrus, bilateral middle occipital gyrus, bilateral inferior occipital gyrus and right superior occipital gyrus; decreased dReHo in bilateral superior occipital gyrus, bilateral cortical area around the talus fissure, and right middle occipital gyrus. CI patients exhibit abnormal activity in multiple brain regions, which can reflect the sleep quality index.

SUPPLEMENTARY INFORMATION

The online version contains supplementary material available at 10.1007/s41105-024-00541-0.

摘要

未标注

探讨慢性失眠(CI)患者的脑功能改变。纳入65例CI患者和48例健康对照,采用静态局部一致性(sReHo)和动态局部一致性(dReHo)方法分析脑自发活动的异常改变。CI患者表现为双侧舌回、双侧枕中回、双侧枕下回和右侧枕上回的sReHo降低;双侧枕上回、距状裂周围双侧皮质区域和右侧枕中回的dReHo降低。CI患者在多个脑区存在异常活动,这可能反映睡眠质量指标。

补充信息

在线版本包含可在10.1007/s41105-024-00541-0获取的补充材料。

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