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将数字疗法与面对面疗法相结合治疗创伤后应激障碍:常规护理中混合式创伤聚焦认知疗法的可行性与可接受性

Integrating digital and in-person therapy for PTSD: feasibility and acceptability of blended trauma-focused cognitive therapy in routine care.

作者信息

Lundin Johan, Jansson-Fröjmark Markus, Gustafsson-Björverud Linda, Grey Nick, Santoft Fredrik, Ehlers Anke, Carlbring Per, Lundgren Tobias, Bragesjö Maria, Salomonsson Sigrid

机构信息

Department of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institute and Stockholm Health Care Services, Stockholm, Sweden.

Sussex Partnership NHS Foundation Trust and School of Psychology, University of Sussex, Brighton, United Kingdom.

出版信息

Front Psychiatry. 2024 Sep 5;15:1447651. doi: 10.3389/fpsyt.2024.1447651. eCollection 2024.

Abstract

INTRODUCTION

Access to evidence-based psychological therapy for posttraumatic stress disorder (PTSD) is limited. Blended Trauma-focused Cognitive Therapy (bTF-CT), merging internet-modules with a few therapy sessions, may be a pathway to enhance treatment access while maintaining the benefits of face-to-face therapy.

OBJECTIVES

This study aimed to evaluate the feasibility, acceptability, and preliminary effectiveness of bTF-CT for PTSD in routine care, as well as the feasibility of assessments and data collection.

METHOD

A single-arm design was adopted. bTF-CT was provided to 17 participants across two psychiatric and one primary care clinic. Assessments were conducted pre, during, post and 6-months following treatment. We assessed feasibility and acceptability via self-report questionnaires, retention, and attrition rates. To estimate preliminary treatment effectiveness the PTSD Symptom Checklist (PCL-5) was used to assess PTSD symptom severity.

RESULTS

Treatment satisfaction was high with a mean score of 28.7 out of 32 on the Client Satisfaction Questionnaire (SD = 3.5). The dropout rate was low, with 88% treatment retention. Program adherence was satisfactory, with scores ranging from 2.13 to 3.13 out of 4 on the internet intervention patient adherence scale. On the PCL-5, 88% made a reliable change, 64% demonstrated a clinically significant change, and the mean change from pre to post was 24 points ( = 2.13). Some negative effects were reported, such as unpleasant memories, feelings, and disrupted sleep, but these were temporary according to symptom scales.

CONCLUSIONS

bTF-CT appears to be acceptable, feasible, and potentially effective when delivered in routine care. A large-scale non-inferiority trial to assess effectiveness compared to a gold-standard treatment is warranted.

CLINICAL TRIAL REGISTRATION

Clinicaltrials.gov, identifier NCT04881643.

摘要

引言

创伤后应激障碍(PTSD)患者获得循证心理治疗的机会有限。混合式创伤聚焦认知疗法(bTF-CT)将网络模块与少量面对面治疗相结合,可能是一种在保持面对面治疗效果的同时增加治疗可及性的途径。

目的

本研究旨在评估bTF-CT在常规护理中治疗PTSD的可行性、可接受性和初步疗效,以及评估和数据收集的可行性。

方法

采用单臂设计。在两家精神科诊所和一家初级保健诊所为17名参与者提供bTF-CT治疗。在治疗前、治疗期间、治疗后及治疗后6个月进行评估。我们通过自我报告问卷、留存率和失访率来评估可行性和可接受性。为评估初步治疗效果,使用创伤后应激障碍症状清单(PCL-5)来评估PTSD症状严重程度。

结果

治疗满意度较高,在患者满意度问卷上的平均得分为28.7分(满分32分,标准差=3.5)。脱落率较低,治疗留存率为88%。在网络干预患者依从性量表上,项目依从性令人满意,得分在4分制中为2.13至3.13分。在PCL-5量表上,88%的患者有可靠的改善,64%的患者有临床显著改善,治疗前到治疗后的平均变化为24分(标准差=2.13)。有一些不良反应报告,如不愉快的记忆、情绪和睡眠中断,但根据症状量表,这些都是暂时的。

结论

bTF-CT在常规护理中应用时似乎是可接受、可行且可能有效的。有必要进行一项大规模非劣效性试验,以评估其与金标准治疗相比的疗效。

临床试验注册

Clinicaltrials.gov,标识符NCT04881643

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f14/11410639/2b68af337c17/fpsyt-15-1447651-g001.jpg

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