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一例心肌沉积物的有趣病例。

An Intriguing Case of Myocardial Deposits.

作者信息

Pawa Arpita, Savani Saloni, Chammany Michael, Mukherjee Saahir, Gayle Kathryn

机构信息

Internal Medicine, Willis Knighton Health, Shreveport, USA.

Medical School, Edward Via College of Osteopathic Medicine, Monroe, USA.

出版信息

Cureus. 2024 Aug 19;16(8):e67226. doi: 10.7759/cureus.67226. eCollection 2024 Aug.

DOI:10.7759/cureus.67226
PMID:39301371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11411393/
Abstract

Cardiac calcification refers to calcium deposits in the coronary arteries, heart valves, pericardium, or myocardium. Calcium deposition within the myocardium is unique and can be secondary to metastatic or dystrophic calcification. Both forms are linked to cardiac abnormalities and poor prognosis. The most common causes include myocardial infarction, sepsis, myocarditis, renal failure, and hyperparathyroidism. Here, we report the case of a 74-year-old male who was found to have gallbladder adenocarcinoma with subsequent preoperative workup indicating possible metastases to the myocardium. With the use of multimodality imaging, particularly cardiac MRI, the differentiation between metastatic disease and intramyocardial calcification was made. The case aims to highlight the complexity of diagnosing and managing myocardial calcifications and underscores the need for further research into their etiology and implications.

摘要

心脏钙化是指冠状动脉、心脏瓣膜、心包或心肌中的钙沉积。心肌内的钙沉积较为独特,可能继发于转移性或营养不良性钙化。这两种形式均与心脏异常及不良预后相关。最常见的病因包括心肌梗死、脓毒症、心肌炎、肾衰竭和甲状旁腺功能亢进。在此,我们报告一例74岁男性患者,其被发现患有胆囊腺癌,随后的术前检查提示可能已转移至心肌。通过使用多模态成像,尤其是心脏磁共振成像,鉴别了转移性疾病和心肌内钙化。该病例旨在突出诊断和处理心肌钙化的复杂性,并强调有必要对其病因及影响进行进一步研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/b92e6793fad0/cureus-0016-00000067226-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/b3e20ff1390c/cureus-0016-00000067226-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/1c5e9e98bc5d/cureus-0016-00000067226-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/c1793cd078de/cureus-0016-00000067226-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/cff9fbdbb0e2/cureus-0016-00000067226-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/4547c9c4b7be/cureus-0016-00000067226-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/da64af4d7c8c/cureus-0016-00000067226-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/b92e6793fad0/cureus-0016-00000067226-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/b3e20ff1390c/cureus-0016-00000067226-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/1c5e9e98bc5d/cureus-0016-00000067226-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/c1793cd078de/cureus-0016-00000067226-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/cff9fbdbb0e2/cureus-0016-00000067226-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/4547c9c4b7be/cureus-0016-00000067226-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/da64af4d7c8c/cureus-0016-00000067226-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8560/11411393/b92e6793fad0/cureus-0016-00000067226-i07.jpg

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本文引用的文献

1
Rapid Onset Development of Myocardial Calcifications in the Setting of Renal Failure and Sepsis.肾衰竭和脓毒症情况下心肌钙化的快速发生发展
Radiol Cardiothorac Imaging. 2021 Apr 1;3(2):e200549. doi: 10.1148/ryct.2021200549. eCollection 2021 Apr.
2
Dystrophic calcification of the interventricular septum mimicking cardiac tumour and role of multimodality imaging.模仿心脏肿瘤的室间隔营养不良性钙化及多模态成像的作用
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Dystrophic Cardiac Calcinosis.
营养不良性心脏钙化
Circ Cardiovasc Imaging. 2020 Mar;13(3):e009978. doi: 10.1161/CIRCIMAGING.119.009978. Epub 2020 Feb 26.
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Dystrophic myocardial calcification.营养不良性心肌钙化
Indian Heart J. 2016 Sep;68 Suppl 2(Suppl 2):S180-S181. doi: 10.1016/j.ihj.2016.02.016. Epub 2016 Feb 28.
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A Curious Case of Acute Myocardial Calcifications.一例急性心肌钙化的罕见病例。
Circulation. 2016 Mar 8;133(10):e426-7. doi: 10.1161/CIRCULATIONAHA.115.019178.
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Cardiovascular magnetic resonance imaging for diagnosis and clinical management of suspected cardiac masses and tumours.心血管磁共振成像在疑似心脏肿块和肿瘤的诊断和临床管理中的应用。
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[Myocardial calcification in chronic renal failure].[慢性肾衰竭中的心肌钙化]
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Massive myocardial calcification and normal coronary arteries.大量心肌钙化且冠状动脉正常。
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Myocardial fibre calcification.心肌纤维钙化
J Clin Pathol. 1981 Oct;34(10):1167-74. doi: 10.1136/jcp.34.10.1167.