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本文引用的文献

1
Acute hepatitis and pancytopenia related to non-typhoidal salmonella infection in a human immunodeficiency virus-infected patient.一名感染人类免疫缺陷病毒的患者出现与非伤寒沙门氏菌感染相关的急性肝炎和全血细胞减少症。
Int J STD AIDS. 2019 Sep;30(10):1034-1036. doi: 10.1177/0956462419863227. Epub 2019 Aug 27.
2
Invasive Nontyphoidal Disease in Africa.非洲侵袭性非伤寒疾病
EcoSal Plus. 2019 Jan;8(2). doi: 10.1128/ecosalplus.ESP-0007-2018.
3
Extraintestinal infections caused by nontyphoidal from a tertiary care center in India.印度一家三级医疗中心非伤寒型肠外感染情况。 （你提供的原文“nontyphoidal ”后面似乎不完整，推测可能是“nontyphoidal Salmonella”之类的表述，这里是按照现有内容尽量通顺翻译的）
J Lab Physicians. 2018 Oct-Dec;10(4):401-405. doi: 10.4103/JLP.JLP_79_18.
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Hepatitis E virus infection.戊型肝炎病毒感染。
Clin Microbiol Rev. 2014 Jan;27(1):116-38. doi: 10.1128/CMR.00057-13.
5
In vitro susceptibility testing of fluoroquinolone activity against Salmonella: recent changes to CLSI standards.体外检测氟喹诺酮类药物对沙门氏菌活性的药敏试验：CLSI 标准的最新变化。
Clin Infect Dis. 2012 Oct;55(8):1107-13. doi: 10.1093/cid/cis600. Epub 2012 Jul 2.
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Abnormalities in liver enzyme levels during Salmonella enteritidis enterocolitis.
Rev Esp Enferm Dig. 2004 Aug;96(8):559-62; 563-6. doi: 10.4321/s1130-01082004000800005.
7
Antimicrobial drug resistance in Salmonella: problems and perspectives in food- and water-borne infections.沙门氏菌中的抗菌药物耐药性：食源性和水源性感染中的问题与展望
FEMS Microbiol Rev. 2002 Jun;26(2):141-8. doi: 10.1111/j.1574-6976.2002.tb00606.x.
8
Special considerations in interpreting liver function tests.肝功能检查解读中的特殊注意事项。
Am Fam Physician. 1999 Apr 15;59(8):2223-30.
9
The spectrum of hepatic injury in enteric fever.伤寒的肝损伤谱
Am J Gastroenterol. 1988 Apr;83(4):413-6.
10
Failure of ciprofloxacin to eradicate convalescent fecal excretion after acute salmonellosis: experience during an outbreak in health care workers.环丙沙星未能根除急性沙门氏菌病后恢复期的粪便排泄：医护人员暴发期间的经验
Ann Intern Med. 1991 Feb 1;114(3):195-9. doi: 10.7326/0003-4819-114-3-195.

非伤寒型肝炎：一种常见肠道感染的罕见并发症。

Nontyphoidal Hepatitis: A Rare Complication of a Common Enteric Infection.

作者信息

Bierowski Matthew J, Edirisuriya Chelsea D, Goldberg Ilana P, Noverati Nicholas, Johnson Peter, Choudhary Cuckoo, Shivashankar Raina

机构信息

Department of Medicine, Thomas Jefferson University, Philadelphia, PA.

Division of Gastroenterology & Hepatology, Thomas Jefferson University, Philadelphia, PA.

出版信息

ACG Case Rep J. 2024 Sep 19;11(9):e01512. doi: 10.14309/crj.0000000000001512. eCollection 2024 Sep.

DOI:10.14309/crj.0000000000001512
PMID:39301461
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11412702/
Abstract

Hepatitis from nontyphoidal gastroenteritis is rare, especially in immunocompetent patients. We present the case of a 30-year-old woman who was found to have serotype C2 gastroenteritis and elevated liver function tests concerning for concurrent hepatitis. An extensive workup was negative for other etiologies, making the likely culprit. The patient was managed with supportive measures as her liver function tests and symptoms were improving before obtaining microbiological data. Since the role of antibiotic therapy in such cases is not well studied, disease severity in accordance with current guidelines should be used to tailor treatment on a case-by-case basis.

摘要

非伤寒性肠胃炎引起的肝炎很罕见，尤其是在免疫功能正常的患者中。我们报告一例30岁女性病例，该患者被发现患有C2血清型肠胃炎且肝功能检查结果升高，提示可能并发肝炎。全面检查排除了其他病因，确定了可能的病因。由于在获得微生物学数据之前患者的肝功能检查和症状正在改善，因此对该患者采取了支持性治疗措施。由于抗生素治疗在这类病例中的作用尚未得到充分研究，应根据当前指南中疾病的严重程度，对每个病例进行个体化治疗。