Paul Biprajit, Ghosh Sayak, Das Surajit, Chatterjee Indranil
Department of Chemistry, Indian Institute of Technology Ropar, Nangal Road, Rupnagar, Punjab-140001, India.
Org Biomol Chem. 2024 Oct 15;22(40):8133-8137. doi: 10.1039/d4ob01382d.
An efficient, eco-friendly, and scalable protocol has been introduced for the -selective C-X (X = Se/S) bond formation of phenols employing earth-abundant, less-toxic Fe(III)-catalysts and the green solvent ethanol without using any directing template, stabilizing ligands, oxidants, or additives. The key attraction lies in the impressive -selectivity with moderate to good yields, wide functional group compatibility under mild aerobic reaction conditions, and the synthetic modification of the products towards value-added molecules.
