Privolzhsky Research Medical University, Nizhny Novgorod, Russia.
Peoples' Friendship University of Russia, Moscow, Russia.
J Biophotonics. 2024 Nov;17(11):e202400318. doi: 10.1002/jbio.202400318. Epub 2024 Sep 20.
While cryotherapy is one of the traditional ways to reduce postoperative complications in maxillofacial surgery, the cooling degree is not regulated in most cases and the achieved effect is not properly controlled. Therefore, to develop optimal cooling modes, we propose to study the buccal vascular response to cooling, which has not been previously shown. To evaluate the effect of cooling, we analyzed vessel networks using optical coherence tomography angiography (OCT-A). The cheek vessels were OCT-A monitored using cooling by an ice bag/cooling mask. We found the advantages of using a cooling mask over an ice bag consist of a statistically significant decrease in the perfused vessel density (PVD) of the papillary layer at the oral mucosa. The absence of the reticular layer vessel reaction to any type of cooling was noted. We argue for the necessity to develop optimal modes of cryotherapy, which will contribute to blood perfusion reduction and reduction of PVD recovery.
冷冻疗法是减少颌面外科术后并发症的传统方法之一，但在大多数情况下，冷却程度没有得到调节，效果也无法得到适当控制。因此，为了开发最佳的冷却模式，我们建议研究颊部血管对冷却的反应，这在以前尚未有过研究。为了评估冷却效果，我们使用光相干断层扫描血管造影术（OCT-A）分析血管网络。使用冰袋/冷却面罩进行冷却，通过 OCT-A 监测颊部血管。我们发现，与冰袋相比，冷却面罩具有统计学意义上的优势，可显著降低口腔黏膜乳头层的血流密度（PVD）。任何类型的冷却都不会引起网状层血管反应。我们认为有必要开发最佳的冷冻疗法模式，这将有助于减少血液灌注和降低 PVD 恢复。
