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先天性并指畸形矫正手术技术的比较:一项系统评价与Meta分析

Comparison Between Surgical Techniques for Correction of Congenital Syndactyly: A Systematic Review and Meta Analysis.

作者信息

Schirlo João Matheus, Saad Cleto André, Beltrame Danilo, Beltrame Mayara, Scortegagna Thais, Marinelli Martins Camila

机构信息

Universidade Estadual de Ponta Grossa, Brazil.

出版信息

Hand (N Y). 2024 Sep 20:15589447241279456. doi: 10.1177/15589447241279456.

Abstract

This review aimed to assess which surgical technique has better outcomes to correct one of the most common congenital anomalies of the upper limb: syndactyly. The following databases were used in the search: PubMed, Embase, Cochrane (CENTRAL), LILACS, SciELO, Scopus and Web of Science, on October 27, 2022. Studies that described a surgical technique for correcting syndactyly and evaluated surgical complications were included. Studies about noncongenital or foot syndactyly were excluded. The risk of bias was assessed using a specific method for case reports. For synthesis of results, the characteristics of the studies and techniques were demonstrated by a qualitative analysis. Meta-analysis models were applied for complications, functionality, and aesthetic. 73 studies were included, of which 70 were series or case reports, 27 studies did not use skin grafts and 7 studies used external fixators. To evaluate functional results, 42 studies used only the surgeon's opinion. Meta-analyses showed a higher incidence of scar defects when using skin grafts and of infection when using external fixators. There was no difference for web creep and readmission. Few studies evaluated results using the VSS scale, showing worse scar pigmentation when skin grafts were used, but there was no difference in other parameters (PROSPERO CRD42022368930).

摘要

本综述旨在评估哪种手术技术在矫正上肢最常见的先天性畸形之一

并指方面具有更好的效果。在2022年10月27日的检索中使用了以下数据库:PubMed、Embase、Cochrane(CENTRAL)、LILACS、SciELO、Scopus和Web of Science。纳入了描述矫正并指手术技术并评估手术并发症的研究。排除了关于非先天性或足部并指的研究。使用针对病例报告的特定方法评估偏倚风险。为了综合结果,通过定性分析展示了研究和技术的特征。对并发症、功能和美观应用了荟萃分析模型。纳入了73项研究,其中70项为系列研究或病例报告,27项研究未使用皮肤移植,7项研究使用了外固定器。为了评估功能结果,42项研究仅采用了外科医生的意见。荟萃分析显示,使用皮肤移植时瘢痕缺损的发生率较高,使用外固定器时感染的发生率较高。在蹼缘增宽和再次入院方面没有差异。很少有研究使用VSS量表评估结果,结果显示使用皮肤移植时瘢痕色素沉着更差,但在其他参数方面没有差异(PROSPERO CRD42022368930)。

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本文引用的文献

1
Syndactyly in the Pediatric Population: A Review of the Literature.儿科人群中的并指畸形:文献综述
Cureus. 2023 Mar 14;15(3):e36118. doi: 10.7759/cureus.36118. eCollection 2023 Mar.
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Treatment of congenital syndactyly.先天性并指畸形的治疗。
Hand Surg Rehabil. 2020 May;39(3):143-153. doi: 10.1016/j.hansur.2019.12.003. Epub 2020 Mar 3.
4
Outcomes of Pediatric Syndactyly Repair Using Synthetic Dermal Substitute.使用合成真皮替代物进行小儿并指修复的结果。
J Hand Surg Am. 2020 Aug;45(8):773.e1-773.e6. doi: 10.1016/j.jhsa.2019.12.005. Epub 2020 Feb 13.
6
How to perform a meta-analysis with R: a practical tutorial.如何使用 R 进行荟萃分析:实用教程。
Evid Based Ment Health. 2019 Nov;22(4):153-160. doi: 10.1136/ebmental-2019-300117. Epub 2019 Sep 28.

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