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[新生儿对听觉刺激近阈值区域的自主反射、脑电图及部分觉醒反应]

[Autonomic reflexes, EEG and partial arousal reaction in the near-threshold region to acoustic stimuli in the newborn].

作者信息

Wranek U, Zwiener U, Eiselt M, Wunder L, Bolwin R

出版信息

EEG EMG Z Elektroenzephalogr Elektromyogr Verwandte Geb. 1985 Jun;16(2):120-3.

PMID:3930212
Abstract

A sample of 19 neonates were exposed to sub- and suprathreshold acoustic stimuli. The experiment was performed with sleeping subjects. Stimuli, tones of 125, 250, 500 and 750 cps, third sounds of the same middle frequency and white noise, were applied only, if periods with no REM activity occurred. Stimulus intensity was varied from the subthreshold level (70-80 dB) to the suprathreshold level (80-100 dB). Polygraphic variables were recorded (EEG, EOG, instantaneous heart rate, respiration movements, actogram, motoric reactions and psychogalvanic reflex). The results showed, that with increasing stimulus intensity irregularities of respiratory parameters occurred. With further increase of stimulus intensity systematic changes in respiratory parameters and heart rate occurred. In addition to these changes, EEG activity and motoric reactions were obtained, when stimulus intensity reached a critical level. These data are consistent with the idea that at low stimulus intensities irregular vegetative reactions occur whereas systematic responses can be observed only, if stimulus intensity is above threshold. We conclude that with increasing stimulus intensity subcortical activity decreases whereas cortical activation increases.

摘要

对19名新生儿进行了阈下和阈上听觉刺激实验。实验在睡眠状态的受试者身上进行。仅在无快速眼动(REM)活动期间施加刺激,刺激包括125、250、500和750赫兹的纯音、相同中频的第三谐音以及白噪声。刺激强度从阈下水平(70 - 80分贝)变化到阈上水平(80 - 100分贝)。记录多导生理变量(脑电图、眼电图、瞬时心率、呼吸运动、活动记录图、运动反应和皮肤电反射)。结果显示,随着刺激强度增加,呼吸参数出现不规则变化。随着刺激强度进一步增加,呼吸参数和心率出现系统性变化。当刺激强度达到临界水平时,除了这些变化外,还观察到脑电图活动和运动反应。这些数据与以下观点一致:在低刺激强度下出现不规则的自主反应,而只有当刺激强度高于阈值时才能观察到系统性反应。我们得出结论,随着刺激强度增加,皮层下活动减少而皮层激活增加。

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