Pollard M J, Megirian D, Sherrey J H
Exp Neurol. 1985 Oct;90(1):187-93. doi: 10.1016/0014-4886(85)90051-2.
In chronically implanted rats, we examined the respiratory EMG activity of the two parts of the diaphragm, costal and crural, during sleep and wakefulness. Their activity was compared and contrasted with that of the EMG activity of the cricothyroid muscle. Whether in wakefulness, while grooming and drinking, or in nonrapid eye movement (non-REM) sleep, and independent of the gas mixture breathed (4 to 5% CO2 or 10% O2 in nitrogen), the two parts of the diaphragm paused during REM apnea episodes whereas the cricothyroid muscle ceased its activity or exhibited sustained activity. We conclude that the diaphragm, mainly an inspiratory muscle, acts as a single functional unit when under the respiratory control system. The cricothyroid muscle functions as an inspiratory and/or expiratory muscle, also under the respiratory control systems. Both muscles in the rat come under other neural control mechanisms governing nonrespiratory functions, e.g., swallowing, defecation, and coughing, but not vomiting.
在长期植入电极的大鼠中，我们研究了在睡眠和清醒状态下，膈肌的肋部和膈部这两个部分的呼吸肌电图（EMG）活动。将它们的活动与环甲肌的肌电图活动进行了比较和对比。无论是在清醒状态下梳理毛发和饮水时，还是在非快速眼动（non-REM）睡眠中，且与所呼吸的气体混合物（氮气中4%至5%的二氧化碳或10%的氧气）无关，在快速眼动睡眠呼吸暂停发作期间，膈肌的两个部分会暂停活动，而环甲肌则停止活动或表现出持续活动。我们得出结论，膈肌主要作为吸气肌，在呼吸控制系统作用下作为一个单一的功能单元发挥作用。环甲肌在呼吸控制系统作用下也作为吸气和/或呼气肌发挥作用。大鼠的这两块肌肉还受其他控制非呼吸功能的神经机制支配，例如吞咽、排便和咳嗽，但不受呕吐支配。
