渤海沉积物中的抗生素耐药基因 (ARGs) 及其生态环境响应。
Antibiotic resistance genes (ARGs) and their eco-environmental response in the Bohai Sea sediments.
机构信息
CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266404, China; University of Chinese Academy of Sciences, Beijing 100049, China.
CAS Key Laboratory of Marine Ecology and Environmental Sciences, Institute of Oceanology, Chinese Academy of Sciences, Qingdao 266404, China; Laboratory for Marine Ecology and Environmental Science, Qingdao Marine Science and Technology Center, Qingdao 266237, China.
出版信息
Mar Pollut Bull. 2024 Nov;208:116979. doi: 10.1016/j.marpolbul.2024.116979. Epub 2024 Sep 19.
Antibiotic resistance genes (ARGs) are an important class of pollutants in the environment. This study investigated the characteristics and ecological effects of ARGs in the Bohai Sea sediments. The results showed that ARGs are widely distributed, and exhibit significant spatial and subtype variations, with absolute abundance following the decreasing order of Liaodong Bay, Laizhou Bay, Bohai Bay, and Bohai Strait. Tetracycline ARGs dominated, comprising 50 % to 62 % of all ARGs, with tetM having the highest abundance at 1.43 × 10 copies/g. Symbiotic network analysis revealed that the phyla Deinococcota, Dadabacteria were serve as the primary likely host of ARGs. The ARGs have a wide range of potential hosts, and bacteria often carry multiple ARGs, enhancing the mobility and ecological niche adaptation of ARGs. This study will provide an important reference for assessing ARGs pollution in semi-enclosed seas.
抗生素耐药基因（ARGs）是环境中一类重要的污染物。本研究调查了渤海沉积物中 ARGs 的特征和生态效应。结果表明，ARGs 广泛分布，具有显著的空间和亚型变异，绝对丰度按辽东湾、莱州湾、渤海湾和渤海海峡的顺序递减。四环素类 ARGs 占主导地位，占所有 ARGs 的 50%至 62%，其中 tetM 的丰度最高，为 1.43×10 拷贝/g。共生网络分析表明，Deinococcota 和 Dadabacteria 门可能是 ARGs 的主要宿主。ARGs 有广泛的潜在宿主，细菌通常携带多个 ARGs，增强了 ARGs 的迁移性和生态位适应性。本研究将为评估半封闭海域 ARGs 污染提供重要参考。
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