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肋间神经冷冻消融联合手术肋骨固定术的住院患者结局。

Inpatient Outcomes of Intercostal Nerve Cryoablation With Surgical Rib Fixation.

机构信息

Division of Trauma, Burns and Surgical Critical Care, Department of Surgery, University of California Irvine, Irvine, California.

Division of Surgical Critical Care, Department of Surgery, University of Connecticut School of Medicine, Farmington, Connecticut.

出版信息

J Surg Res. 2024 Nov;303:105-110. doi: 10.1016/j.jss.2024.08.022. Epub 2024 Sep 19.

Abstract

INTRODUCTION

Rib fractures are associated with significant pain and morbidity. Intercostal nerve cryoablation (INCA) offers targeted, prolonged pain relief for these patients. Over the last decade, more patients have undergone surgical stabilization of rib fractures (SSRF) after injury. However, data on INCA use in SSRF patients are limited. This study aimed to identify the relationship of INCA in blunt trauma patients (BTPs) undergoing SSRF, hypothesizing INCA coupled with SSRF would decrease hospital length of stay (LOS).

METHODS

The Trauma Quality Improvement Program database (2017-2021) was queried for BTPs ≥18 y old who underwent SSRF. Patients who received INCA ((+)INCA) were compared to patients who did not ((-)INCA). The primary outcome was LOS. Secondary outcomes included intensive care unit (ICU) LOS and in-hospital complications. A subgroup analysis of only flail chest patients was performed.

RESULTS

From 15,784 BTPs, 750 (4.8%) received INCA. Hospital LOS was similar between groups (12 versus 12 d, P = 0.10); however, the (+)INCA patients had decreased ICU LOS (6 versus 7 d, P < 0.001). The (+)INCA cohort also had decreased hospital complications (20.4% versus 24.4%, P = 0.01), including pulmonary embolism (0.7% versus 1.8%, P = 0.02) and ventilator-associated pneumonia (2.1% versus 3.8%, P = 0.02). On subgroup analysis of flail chest patients, decreased ICU LOS in the (+)INCA patients remained a significant outcome (7 versus 8 d, P = 0.02).

CONCLUSIONS

Nearly 5% of SSRF patients received INCA. While overall LOS was similar, the (+)INCA cohort had decreased ICU LOS and in-hospital complications. Future studies are needed to corroborate these findings and evaluate any long-term complications associated with INCA before widespread adoption.

摘要

简介

肋骨骨折会引起严重的疼痛和发病。肋间神经冷冻消融术(INCA)为这些患者提供了针对性的、长期的疼痛缓解。在过去的十年中,越来越多的肋骨骨折患者在受伤后接受了外科固定术(SSRF)。然而,关于 INCA 在 SSRF 患者中的应用数据有限。本研究旨在确定 INCA 在钝性创伤患者(BTP)接受 SSRF 中的关系,假设 INCA 与 SSRF 相结合会缩短住院时间(LOS)。

方法

使用创伤质量改进计划数据库(2017-2021 年),对接受 SSRF 的年龄≥18 岁的 BTP 患者进行了查询。比较了接受 INCA 治疗的患者(+INCA)和未接受 INCA 治疗的患者(-INCA)。主要结局是 LOS。次要结局包括重症监护病房(ICU)LOS 和院内并发症。还对只有连枷胸患者进行了亚组分析。

结果

在 15784 名 BTP 中,有 750 名(4.8%)接受了 INCA 治疗。两组患者的住院 LOS 相似(12 天对 12 天,P=0.10);然而,+INCA 患者的 ICU LOS 降低(6 天对 7 天,P<0.001)。+INCA 组的院内并发症发生率也降低(20.4%对 24.4%,P=0.01),包括肺栓塞(0.7%对 1.8%,P=0.02)和呼吸机相关性肺炎(2.1%对 3.8%,P=0.02)。在连枷胸患者的亚组分析中,+INCA 患者的 ICU LOS 降低仍然是一个显著的结果(7 天对 8 天,P=0.02)。

结论

近 5%的 SSRF 患者接受了 INCA 治疗。虽然总 LOS 相似,但+INCA 组的 ICU LOS 和院内并发症减少。需要进一步的研究来证实这些发现,并在广泛应用之前评估 INCA 相关的任何长期并发症。

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