从寒冷中恢复：Rho 依赖性终止有助于适应冷休克。
Coming in out of the cold: Rho-dependent termination contributes to adaptation to cold shock.
机构信息
Institute for Advanced Biosciences, Keio University, Tsuruoka, Yamagata 997-0017, Japan.
Laboratory of Molecular Biology, Center for Cancer Research, NCI, Bethesda, MD 20892, USA.
出版信息
Mol Cell. 2024 Sep 19;84(18):3373-3374. doi: 10.1016/j.molcel.2024.08.033.
PMID:39303677
Abstract
During cold shock, bacteria shut down translation of all but a set of cold-shock proteins critical for recovery; in this issue of Molecular Cell, Delaleau et al. show that Rho-dependent transcription termination plays an important role in cold adaptation, via temperature-regulated termination of the cold-shock protein mRNAs.
摘要
在冷休克期间，细菌会关闭除了一组对恢复至关重要的冷休克蛋白之外的所有翻译；在本期《分子细胞》中，Deleau 等人表明，Rho 依赖性转录终止在冷适应中发挥重要作用，这是通过温度调节冷休克蛋白 mRNA 的终止实现的。
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