Kulkarni A G, Ibazebo R O, Dunn D T, Fleming A F
Hum Hered. 1985;35(5):283-7. doi: 10.1159/000153563.
The A, B, O, D, Du, C, c, E, e, M, N, S, s, Kell and Duffy antigens were determined on 190 blood samples from Hausas in the north of Nigeria. The highest gene frequencies in the rhesus system were cDe (0.648) and cde (0.176). Su gene frequency was 0.270. The great majority of subjects were Kell negative (98.9%) and Duffy negative (98.8%). As the MNSs group determinants are carried by glycophorins, which are also receptor sites for Plasmodium falciparum, and the Duffy antigen marks the receptor for P. vivax, the present study provides data of interest in the epidemiology and genetics of malaria.
对来自尼日利亚北部豪萨族的190份血样进行了A、B、O、D、Du、C、c、E、e、M、N、S、s、凯尔(Kell)和达菲(Duffy)抗原检测。恒河猴系统中最高的基因频率是cDe(0.648)和cde(0.176)。Su基因频率为0.270。绝大多数研究对象凯尔抗原呈阴性(98.9%),达菲抗原呈阴性(98.8%)。由于MNSs组决定簇由血型糖蛋白携带,而血型糖蛋白也是恶性疟原虫的受体位点,且达菲抗原是间日疟原虫的受体标记,因此本研究提供了有关疟疾流行病学和遗传学的有趣数据。