Scully Aileen Eugenia, Tan Dawn May Leng, de Oliveira Beatriz Ito Ramos, Hill Keith David, Clark Ross, Pua Yong Hao
Health and Social Sciences, Singapore Institute of Technology, Singapore.
Health and Social Sciences, Singapore Institute of Technology, Singapore; Department of Physiotherapy, Singapore General Hospital, Singapore.
Arch Phys Med Rehabil. 2025 Feb;106(2):247-254. doi: 10.1016/j.apmr.2024.09.003. Epub 2024 Sep 18.
To provide an easy-to-use measure, as existing objective assessments for freezing of gait (FOG) severity may be unwieldy for routine clinical practice, this study explored time taken to complete the recently validated FOG severity tool and its components.
A cross-sectional study.
Outpatient clinics of a tertiary hospital.
People with Parkinson disease who could independently ambulate 8-meters, understand instructions, and without co-morbidities affecting gait were consecutively recruited. Thirty-five participants were included (82.9% [n=29] male; median [IQR]: age of 73.0 [11.0] years and disease duration of 4.0 [4.5] years).
Not applicable.
Participants were assessed with the FOG severity tool in a test-retest design, with time taken for each component recorded using a stopwatch during video-analysis. Validity of total FOG severity tool time, time taken to complete its turning and narrow-space components (i.e., time to navigate [TTN]), and an adjusted TTN were examined through correlations with validated FOG severity outcomes. To facilitate clinical interpretation, the TTN cut-off was determined using scatterplot smoothing regression, whereas minimal important change was calculated using predictive modeling.
The FOG severity tool time, TTN, and adjusted TTN similarly demonstrated moderate correlations with the FOG questionnaire and percentage-FOG, and very high correlations with FOG severity tool-revised. The TTN was nonlinearly related to FOG severity, with a positive relationship observed in the first 300 seconds and plateauing after. minimal important change for TTN was 15.4 seconds reduction in timing (95% CI, 3.2-28.7).
The TTN is a feasible, interpretable, and valid test of FOG severity. In busy clinical settings, TTN can provide a viable alternative when use of existing objective FOG measures is (often) unfeasible.
由于现有的步态冻结（FOG）严重程度客观评估方法在常规临床实践中可能不太实用，本研究旨在探索完成最近验证的FOG严重程度工具及其组件所需的时间，以提供一种易于使用的测量方法。
横断面研究。
一家三级医院的门诊诊所。
连续招募能够独立行走8米、理解指令且无影响步态的合并症的帕金森病患者。纳入了35名参与者（男性占82.9%[n = 29]；中位数[四分位间距]：年龄73.0[11.0]岁，病程4.0[4.5]年）。
不适用。
采用重测设计，使用FOG严重程度工具对参与者进行评估，在视频分析过程中用秒表记录每个组件所需的时间。通过与验证的FOG严重程度结果的相关性，检验总FOG严重程度工具时间、完成其转弯和狭窄空间组件所需的时间（即导航时间[TTN]）以及调整后的TTN的有效性。为便于临床解释，使用散点图平滑回归确定TTN临界值，而使用预测模型计算最小重要变化。
FOG严重程度工具时间、TTN和调整后的TTN与FOG问卷和FOG百分比同样呈现中等相关性，与修订后的FOG严重程度工具呈现非常高的相关性。TTN与FOG严重程度呈非线性关系，在前300秒观察到正相关，之后趋于平稳。TTN的最小重要变化是时间减少15.4秒（95%CI，3.2 - 28.7）。
TTN是一种可行、可解释且有效的FOG严重程度测试方法。在繁忙的临床环境中，当使用现有的客观FOG测量方法（通常）不可行时，TTN可以提供一个可行的替代方案。
